CD8 T-cell Recruitment Into the Central Nervous System of Cuprizone-Fed Mice: Relevance to Modeling the Etiology of Multiple Sclerosis

Cuprizone (CPZ)-feeding in mice induces atrophy of peripheral immune organs (thymus and spleen) and suppresses T-cell levels, thereby limiting its use as a model for studying the effects of the immune system in demyelinating diseases such as Multiple Sclerosis (MS). To investigate whether castration...

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Detalles Bibliográficos
Autores principales: Almuslehi, Mohammed S. M., Sen, Monokesh K., Shortland, Peter J., Mahns, David A., Coorssen, Jens R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076139/
https://www.ncbi.nlm.nih.gov/pubmed/32210765
http://dx.doi.org/10.3389/fncel.2020.00043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076139/
https://www.ncbi.nlm.nih.gov/pubmed/32210765
http://dx.doi.org/10.3389/fncel.2020.00043

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