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Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products

Thrombin-derived C-terminal peptides (TCPs), including a major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli. However, the physiological roles of TCP96 in controlling bacteri...

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Detalles Bibliográficos
Autores principales:	Petrlova, Jitka, Petruk, Ganna, Huber, Roland G., McBurnie, Eilish W., van der Plas, Mariena J. A., Bond, Peter J., Puthia, Manoj, Schmidtchen, Artur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076200/ https://www.ncbi.nlm.nih.gov/pubmed/32034093 http://dx.doi.org/10.1074/jbc.RA120.012741

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