Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2–AS1

Hyaluronan (HA) is one of the most prevalent glycosaminoglycans of the vascular extracellular matrix (ECM). Abnormal HA accumulation within blood vessel walls is associated with tissue inflammation and is prominent in most vascular pathological conditions such as atherosclerosis and restenosis. Hyal...

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Detalles Bibliográficos
Autores principales: Caon, Ilaria, Bartolini, Barbara, Moretto, Paola, Parnigoni, Arianna, Caravà, Elena, Vitale, Daiana L., Alaniz, Laura, Viola, Manuela, Karousou, Evgenia, De Luca, Giancarlo, Hascall, Vincent C., Passi, Alberto, Vigetti, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076221/
https://www.ncbi.nlm.nih.gov/pubmed/31932306
http://dx.doi.org/10.1074/jbc.RA119.011982

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