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The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review
Human enamel once formed cannot be biologically repaired or replaced. Saliva has a significant role in remineralization of dental enamel. It not only has a buffering capacity to neutralize the oral cavity’s low pH generated after acidic encounters, but also acts as a carrier of essential ions, such...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076334/ https://www.ncbi.nlm.nih.gov/pubmed/32201577 http://dx.doi.org/10.12688/f1000research.22499.3 |
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author | Farooq, Imran Bugshan, Amr |
author_facet | Farooq, Imran Bugshan, Amr |
author_sort | Farooq, Imran |
collection | PubMed |
description | Human enamel once formed cannot be biologically repaired or replaced. Saliva has a significant role in remineralization of dental enamel. It not only has a buffering capacity to neutralize the oral cavity’s low pH generated after acidic encounters, but also acts as a carrier of essential ions, such as fluoride, calcium and phosphate, which have a positive role in enamel’s remineralization. This review discusses how salivary contents, like proteins and enzymes, have a natural role in enamel’s mineralization. In addition, the presence of ions, such as fluoride, calcium and phosphate, in saliva further enhances its capability to remineralize the demineralized enamel surface. The review further examines modern innovative technologies, based on biomimetic regeneration systems, including dentin phosphoproteins, aspartate-serine-serine, recombinant porcine amelogenin, leucine-rich amelogenin peptide and nano-hydroxyapatite, that promote enamel remineralization. Fluoride boosters like calcium phosphates, polyphosphates, and certain natural products can also play an important role in enamel remineralization. |
format | Online Article Text |
id | pubmed-7076334 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-70763342020-03-20 The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review Farooq, Imran Bugshan, Amr F1000Res Review Human enamel once formed cannot be biologically repaired or replaced. Saliva has a significant role in remineralization of dental enamel. It not only has a buffering capacity to neutralize the oral cavity’s low pH generated after acidic encounters, but also acts as a carrier of essential ions, such as fluoride, calcium and phosphate, which have a positive role in enamel’s remineralization. This review discusses how salivary contents, like proteins and enzymes, have a natural role in enamel’s mineralization. In addition, the presence of ions, such as fluoride, calcium and phosphate, in saliva further enhances its capability to remineralize the demineralized enamel surface. The review further examines modern innovative technologies, based on biomimetic regeneration systems, including dentin phosphoproteins, aspartate-serine-serine, recombinant porcine amelogenin, leucine-rich amelogenin peptide and nano-hydroxyapatite, that promote enamel remineralization. Fluoride boosters like calcium phosphates, polyphosphates, and certain natural products can also play an important role in enamel remineralization. F1000 Research Limited 2021-06-15 /pmc/articles/PMC7076334/ /pubmed/32201577 http://dx.doi.org/10.12688/f1000research.22499.3 Text en Copyright: © 2021 Farooq I and Bugshan A https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Farooq, Imran Bugshan, Amr The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title | The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title_full | The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title_fullStr | The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title_full_unstemmed | The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title_short | The role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
title_sort | role of salivary contents and modern technologies in the remineralization of dental enamel: a narrative review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076334/ https://www.ncbi.nlm.nih.gov/pubmed/32201577 http://dx.doi.org/10.12688/f1000research.22499.3 |
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