Cargando…

Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats

Peptic ulcer disease is an injury of the alimentary tract that leads to a mucosal defect reaching the submucosa. This study aimed to formulate and optimize omega-3 oil as a self-nanoemulsifying drug delivery system (SNEDDS) to achieve oil dispersion in the nano-range in the stomach to augment omega-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmed, Osama A. A., Fahmy, Usama A., Bakhaidar, Rana, El-Moselhy, Mohamed A., Okbazghi, Solomon Z., Ahmed, Al-Shaimaa F., Hammad, Asmaa S. A., Alhakamy, Nabil A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076357/ https://www.ncbi.nlm.nih.gov/pubmed/32045979 http://dx.doi.org/10.3390/pharmaceutics12020140

Ejemplares similares

Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats
por: Ahmed, Osama A A, et al.
Publicado: (2020)

Optimized Self-Nanoemulsifying Delivery System Based on Plant-Derived Oil Augments Alpha-Lipoic Acid Protective Effects Against Experimentally Induced Gastric Lesions
por: Badr-Eldin, Shaimaa M., et al.
Publicado: (2021)

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer
por: Radwan, Mohamed F., et al.
Publicado: (2021)

Attenuation of Benign Prostatic Hyperplasia by Optimized Tadalafil Loaded Pumpkin Seed Oil-Based Self Nanoemulsion: In Vitro and In Vivo Evaluation
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Green Nanoemulsion Stabilized by In Situ Self-Assembled Natural Oil/Native Cyclodextrin Complexes: An Eco-Friendly Approach for Enhancing Anticancer Activity of Costunolide against Lung Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

Development of omega-3 loxoprofen-loaded nanoemulsion to limit the side effect associated with NSAIDs in treatment of tooth pain
por: Hosny, Khaled M., et al.
Publicado: (2021)

Two-Step Optimization to Develop a Transdermal Film Loaded With Dapoxetine Nanoparticles: A Promising Technique to Improve Drug Skin Permeation
por: Ahmed, Tarek A., et al.
Publicado: (2020)

Novel Nanoconjugate of Apamin and Ceftriaxone for Management of Diabetic Wounds
por: Alamoudi, Abdullah A., et al.
Publicado: (2022)

Scorpion Venom-Functionalized Quercetin Phytosomes for Breast Cancer Management: In Vitro Response Surface Optimization and Anticancer Activity against MCF-7 Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Optimized Nanostructured Lipid Carriers Integrated into In Situ Nasal Gel for Enhancing Brain Delivery of Flibanserin
por: Fahmy, Usama A, et al.
Publicado: (2020)

Fluoxetine Ecofriendly Nanoemulsion Enhances Wound Healing in Diabetic Rats: In Vivo Efficacy Assessment
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

Development and In Vitro Evaluation of 2-Methoxyestradiol Loaded Polymeric Micelles for Enhancing Anticancer Activities in Prostate Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Apamin-Conjugated Alendronate Sodium Nanocomplex for Management of Pancreatic Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Mastoparan, a Peptide Toxin from Wasp Venom Conjugated Fluvastatin Nanocomplex for Suppression of Lung Cancer Cell Growth
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment
por: Aldawsari, Hibah M., et al.
Publicado: (2021)

Role of Rosiglitazone as a Gastroprotective Agent Against Indomethacin-Induced Gastric Mucosal Injury in Rats
por: Taye, Ashraf, et al.
Publicado: (2009)

Adverse Events and Tolerability of Combined Durvalumab and Tremelimumab versus Durvalumab Alone in Solid Cancers: A Systematic Review and Meta-Analysis
por: Fahmy, Omar, et al.
Publicado: (2022)

Gastroprotective effect of methanolic extract of Gomphrena celosioides on indomethacin induced gastric ulcer in Wistar albino rats
por: Oluwabunmi, Ige Janet, et al.
Publicado: (2015)

Gastroprotective Effect of Enteral Nutrition Formula in Mice Injected Subcutaneously with Indomethacin
por: Yamagishi, Yoshiaki, et al.
Publicado: (2021)

Optimized Icariin Cubosomes Exhibit Augmented Cytotoxicity against SKOV-3 Ovarian Cancer Cells
por: Fahmy, Usama A., et al.
Publicado: (2020)

Optimized Apamin-Mediated Nano-Lipidic Carrier Potentially Enhances the Cytotoxicity of Ellagic Acid against Human Breast Cancer Cells
por: Badr-Eldin, Shaimaa M., et al.
Publicado: (2022)

Formulation, Optimization, and Evaluation of Oregano Oil Nanoemulsions for the Treatment of Infections Due to Oral Microbiota
por: Hosny, Khaled, et al.
Publicado: (2021)

The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells
por: Fahmy, Usama A., et al.
Publicado: (2020)

Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2020)

Fabrication, assessment, and optimization of alendronate sodium nanoemulsion-based injectable in-situ gel formulation for management of osteoporosis
por: Abdulaal, Wesam H., et al.
Publicado: (2023)

Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer
por: Aldawsari, Hibah M., et al.
Publicado: (2021)

Optimization of the Factors Affecting the Absorption of Vardenafil from Oral Disintegrating Tablets: A Clinical Pharmacokinetic Investigation
por: Al-Gethmy, Hytham A., et al.
Publicado: (2019)

Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats
por: Asfour, Hani Z., et al.
Publicado: (2022)

Oncological Response and Predictive Biomarkers for the Checkpoint Inhibitors in Castration-Resistant Metastatic Prostate Cancer: A Systematic Review and Meta-Analysis
por: Fahmy, Omar, et al.
Publicado: (2021)

Preparation and In Vivo Evaluation of Indomethacin Loaded True Nanoemulsions
por: Shakeel, Faiyaz, et al.
Publicado: (2010)

Gastroprotective Effects of Spirulina platensis, Golden Kiwifruit Flesh, and Golden Kiwifruit Peel Extracts Individually or in Combination against Indomethacin-Induced Gastric Ulcer in Rats
por: Aleid, Ibrahim S., et al.
Publicado: (2021)

Gastroprotective effects of both aqueous and ethanolic extracts of Lemon verbena leaves against indomethacin-induced gastric ulcer in rats
por: Mashayekhi-sardoo, Habibeh, et al.
Publicado: (2020)

Gastroprotective effect of zafirlukast against indomethacin induced gastric ulcer in rats via PGE2 and anti-inflammatory pathways
por: Aal-Aaboda, Munaf, et al.
Publicado: (2023)

Enhanced healing efficacy of an optimized gabapentin-melittin nanoconjugate gel-loaded formulation in excised wounds of diabetic rats
por: Asfour, Hani Z., et al.
Publicado: (2022)

Adenosine Conjugated Docetaxel Nanoparticles—Proof of Concept Studies for Non-Small Cell Lung Cancer
por: Aldawsari, Hibah M., et al.
Publicado: (2022)

Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles
por: Al-Rabia, Mohammed W., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qfn2umojr9jtrbmfu4l9du56vp