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Development of an In Vitro System to Study the Interactions of Aerosolized Drugs with Pulmonary Mucus

Mucus is the first biological component inhaled drugs encounter on their journey towards their pharmacological target in the upper airways. Yet, how mucus may influence drug disposition and efficacy in the lungs has been essentially overlooked. In this study, a simple in vitro system was developed t...

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Detalles Bibliográficos
Autores principales: Alqahtani, Safar, Roberts, Clive J., Stolnik, Snjezana, Bosquillon, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076363/
https://www.ncbi.nlm.nih.gov/pubmed/32053877
http://dx.doi.org/10.3390/pharmaceutics12020145