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Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles
Alternative routes of administration are one approach that could be used to bypass the blood–brain barrier (BBB) for effective drug delivery to the central nervous system (CNS). Here, we focused on intranasal delivery of polymer nanoparticles. We hypothesized that surface modification of poly(lactic...
Autores principales: | Chung, Eugene P., Cotter, Jennifer D., Prakapenka, Alesia V., Cook, Rebecca L., DiPerna, Danielle M., Sirianni, Rachael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076461/ https://www.ncbi.nlm.nih.gov/pubmed/31991664 http://dx.doi.org/10.3390/pharmaceutics12020093 |
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