Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Ischemic stroke is the 5th leading cause of death in the United States. Despite significant improvements in reperfusion therapies, stroke patients still suffer from debilitating neurocognitive deficits. This indicates an essential need to develop novel stroke treatment paradigms. Endogenous uptake t...

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Detalles Bibliográficos
Autores principales: Williams, Erica I., Betterton, Robert D., Davis, Thomas P., Ronaldson, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076465/
https://www.ncbi.nlm.nih.gov/pubmed/32075088
http://dx.doi.org/10.3390/pharmaceutics12020154

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