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Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity

Long-acting preparations containing the antipsychotic paliperidone for intramuscular injection has drawn considerable attention to achieve harmless long-term treatment. This study aimed to develop paliperidone loaded polycaprolactone (PCL) nanoparticles and investigate the influence of PCL/drug rati...

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Detalles Bibliográficos
Autores principales:	Elmowafy, Mohammed, Alruwaili, Nabil K., Shalaby, Khaled, Alharbi, Khalid S., Altowayan, Waleed M., Ahmad, Naveed, Zafar, Ameeduzzafar, Elkomy, Mohammed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076490/ https://www.ncbi.nlm.nih.gov/pubmed/32079093 http://dx.doi.org/10.3390/pharmaceutics12020160

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