Cargando…

Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles to increase the permeability of cell membranes. We assessed gemcitabine up...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bjånes, Tormod, Kotopoulis, Spiros, Murvold, Elisa Thodesen, Kamčeva, Tina, Gjertsen, Bjørn Tore, Gilja, Odd Helge, Schjøtt, Jan, Riedel, Bettina, McCormack, Emmet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076495/ https://www.ncbi.nlm.nih.gov/pubmed/32046005 http://dx.doi.org/10.3390/pharmaceutics12020141

Ejemplares similares

Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells
por: Haugse, Ragnhild, et al.
Publicado: (2020)

SonoVue(®) vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
por: Kotopoulis, Spiros, et al.
Publicado: (2022)

Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys
por: Eikrem, Oystein, et al.
Publicado: (2021)

Intracellular Signaling in Key Pathways Is Induced by Treatment with Ultrasound and Microbubbles in a Leukemia Cell Line, but Not in Healthy Peripheral Blood Mononuclear Cells
por: Haugse, Ragnhild, et al.
Publicado: (2019)

Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery
por: Kotopoulis, Spiros, et al.
Publicado: (2022)

Perception of prescribing factors and purchase statistics of non-steroidal anti-inflammatory drugs in an orthopedic clinic
por: Schjøtt, Jan, et al.
Publicado: (2020)

The HDACi Panobinostat Shows Growth Inhibition Both In Vitro and in a Bioluminescent Orthotopic Surgical Xenograft Model of Ovarian Cancer
por: Helland, Øystein, et al.
Publicado: (2016)

First In-Mouse Development and Application of a Surgically Relevant Xenograft Model of Ovarian Carcinoma
por: Helland, Øystein, et al.
Publicado: (2014)

p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy
por: Haaland, Ingvild, et al.
Publicado: (2021)

Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid
por: Forthun, Rakel Brendsdal, et al.
Publicado: (2012)

Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia
por: Forthun, Rakel Brendsdal, et al.
Publicado: (2019)

Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia
por: Leitch, Calum, et al.
Publicado: (2016)

Up-regulation of anti-apoptotic genes confers resistance to the novel anti-leukaemic compound PEP005 in primary AML cells
por: Hampson, Peter, et al.
Publicado: (2014)

Expression of TP53 Isoforms p53β or p53γ Enhances Chemosensitivity in TP53(null) Cell Lines
por: Silden, Elisabeth, et al.
Publicado: (2013)

High expression of the p53 isoform γ is associated with reduced progression-free survival in uterine serous carcinoma
por: Bischof, Katharina, et al.
Publicado: (2018)

Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods
por: Anandan, Shamundeeswari, et al.
Publicado: (2021)

Point-of-care Ultrasound of the Gastrointestinal Tract
por: Gilja, Odd Helge, et al.
Publicado: (2023)

Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia
por: Haaland, Ingvild, et al.
Publicado: (2014)

Abnormalities in ileal stem, neurogenin 3, and enteroendocrine cells in patients with irritable bowel syndrome
por: El-Salhy, Magdy, et al.
Publicado: (2017)

Chromogranin A cells in the stomachs of patients with sporadic irritable bowel syndrome
por: EL-SALHY, MAGDY, et al.
Publicado: (2014)

Increased wall thickness using ultrasonography is associated with inflammation in an animal model of experimental colitis
por: Lied, Gülen Arslan, et al.
Publicado: (2012)

CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
por: Kleinmanns, Katrin, et al.
Publicado: (2020)

Overlapping of irritable bowel syndrome with erosive esophagitis and the performance of Rome criteria in diagnosing IBS in a clinical setting
por: El-Salhy, Magdy, et al.
Publicado: (2019)

Abnormalities in endocrine and immune cells are correlated in dextran-sulfate-sodium-induced colitis in rats
por: El-Salhy, Magdy, et al.
Publicado: (2017)

Optimal treatment occasion for ultrasound stimulated microbubbles in promoting gemcitabine delivery to VX2 tumors
por: Luo, Tingting, et al.
Publicado: (2022)

Enteroendocrine cells, stem cells and differentiation progenitors in rats with TNBS-induced colitis
por: El-Salhy, Magdy, et al.
Publicado: (2016)

Healthcare professionals’ information need related to antiseizure medication use in breastfeeding patients with epilepsy. Retrospective analysis of enquiries to Norwegian medicines information and pharmacovigilance centers
por: Reitan Riibe, Sunniva, et al.
Publicado: (2023)

Stomach antral endocrine cells in patients with irritable bowel syndrome
por: EL-SALHY, MAGDY, et al.
Publicado: (2014)

The relation between celiac disease, nonceliac gluten sensitivity and irritable bowel syndrome
por: El-Salhy, Magdy, et al.
Publicado: (2015)

Abnormal differentiation of stem cells into enteroendocrine cells in rats with DSS-induced colitis
por: El-Salhy, Magdy, et al.
Publicado: (2017)

Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids
por: Berg, Jon Andsnes, et al.
Publicado: (2015)

Development and Validation of a Simple Ultrasound Activity Score for Crohn’s Disease
por: Sævik, Fredrik, et al.
Publicado: (2020)

Assessment of Small Bowel Motility and SMA Blood Flow Studied with Transabdominal Ultrasound
por: Nylund, Kim, et al.
Publicado: (2022)

Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia
por: Andresen, Vibeke, et al.
Publicado: (2016)

The Emerging Role of CD24 in Cancer Theranostics—A Novel Target for Fluorescence Image-Guided Surgery in Ovarian Cancer and Beyond
por: Kleinmanns, Katrin, et al.
Publicado: (2020)

Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
por: EL-SALHY, MAGDY, et al.
Publicado: (2014)

Duodenal Chromogranin A Cell Density as a Biomarker for the Diagnosis of Irritable Bowel Syndrome
por: El-Salhy, Magdy, et al.
Publicado: (2014)

Fecal Fat Analyses in Chronic Pancreatitis Importance of Fat Ingestion before Stool Collection
por: Erchinger, Friedemann, et al.
Publicado: (2017)

Repeatability of shear wave elastography in liver fibrosis phantoms—Evaluation of five different systems
por: Mulabecirovic, Anesa, et al.
Publicado: (2018)

Liver elasticity in healthy individuals by two novel shear-wave elastography systems—Comparison by age, gender, BMI and number of measurements
por: Mulabecirovic, Anesa, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nesuc6m55ltq41en4novg1h2l8