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Development of Meloxicam-Human Serum Albumin Nanoparticles for Nose-to-Brain Delivery via Application of a Quality by Design Approach

The aim of this study was to optimize the formulation of meloxicam (MEL)-containing human serum albumin (HSA) nanoparticles for nose-to-brain via a quality by design (QbD) approach. Liquid and dried formulations of nanoparticles containing Tween 80 and without the surfactant were investigated. Vario...

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Detalles Bibliográficos
Autores principales: Katona, Gábor, Balogh, György Tibor, Dargó, Gergő, Gáspár, Róbert, Márki, Árpád, Ducza, Eszter, Sztojkov-Ivanov, Anita, Tömösi, Ferenc, Kecskeméti, Gábor, Janáky, Tamás, Kiss, Tamás, Ambrus, Rita, Pallagi, Edina, Szabó-Révész, Piroska, Csóka, Ildikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076499/
https://www.ncbi.nlm.nih.gov/pubmed/31991767
http://dx.doi.org/10.3390/pharmaceutics12020097