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Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging
Antimicrobial medicine and food packages based on bio-based film containing essential oils have attracted great attention worldwide. However, the controlled release of essential oils from these film nanocomposites is still a big challenge. In this study, a long-term antibacterial film nanocomposite...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076511/ https://www.ncbi.nlm.nih.gov/pubmed/32085384 http://dx.doi.org/10.3390/pharmaceutics12020169 |
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author | Liu, Xiaojing Jia, Jingfu Duan, Shulei Zhou, Xue Xiang, Anya Lian, Ziling Ge, Fahuan |
author_facet | Liu, Xiaojing Jia, Jingfu Duan, Shulei Zhou, Xue Xiang, Anya Lian, Ziling Ge, Fahuan |
author_sort | Liu, Xiaojing |
collection | PubMed |
description | Antimicrobial medicine and food packages based on bio-based film containing essential oils have attracted great attention worldwide. However, the controlled release of essential oils from these film nanocomposites is still a big challenge. In this study, a long-term antibacterial film nanocomposite composed of zein film and cinnamon essential oil (CEO) loaded MCM-41 silica nanoparticles was prepared. The CEO was loaded into MCM-41 particles via modified supercritical impregnation efficiently with a high drug load (>40 wt%). The morphologies of the prepared nanoparticles and film nanocomposite were characterized by a scanning electron microscope. The release behaviors of CEO under different temperatures, high humidity, continuous illumination and in phosphate buffer solution (PBS) solution were investigated. The results showed that the film nanocomposite had an outstanding release-control effect. The addition of MCM-41 nanoparticles also improved the mechanical properties of zein films. The antibacterial effect of CEO was significantly prolonged by the film nanocomposite; indicating the CEO film nanocomposite fabricated via modified supercritical CO(2) impregnation was a potential long-term antibacterial medicine or food package material. |
format | Online Article Text |
id | pubmed-7076511 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70765112020-03-20 Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging Liu, Xiaojing Jia, Jingfu Duan, Shulei Zhou, Xue Xiang, Anya Lian, Ziling Ge, Fahuan Pharmaceutics Article Antimicrobial medicine and food packages based on bio-based film containing essential oils have attracted great attention worldwide. However, the controlled release of essential oils from these film nanocomposites is still a big challenge. In this study, a long-term antibacterial film nanocomposite composed of zein film and cinnamon essential oil (CEO) loaded MCM-41 silica nanoparticles was prepared. The CEO was loaded into MCM-41 particles via modified supercritical impregnation efficiently with a high drug load (>40 wt%). The morphologies of the prepared nanoparticles and film nanocomposite were characterized by a scanning electron microscope. The release behaviors of CEO under different temperatures, high humidity, continuous illumination and in phosphate buffer solution (PBS) solution were investigated. The results showed that the film nanocomposite had an outstanding release-control effect. The addition of MCM-41 nanoparticles also improved the mechanical properties of zein films. The antibacterial effect of CEO was significantly prolonged by the film nanocomposite; indicating the CEO film nanocomposite fabricated via modified supercritical CO(2) impregnation was a potential long-term antibacterial medicine or food package material. MDPI 2020-02-18 /pmc/articles/PMC7076511/ /pubmed/32085384 http://dx.doi.org/10.3390/pharmaceutics12020169 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Liu, Xiaojing Jia, Jingfu Duan, Shulei Zhou, Xue Xiang, Anya Lian, Ziling Ge, Fahuan Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title | Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title_full | Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title_fullStr | Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title_full_unstemmed | Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title_short | Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging |
title_sort | zein/mcm-41 nanocomposite film incorporated with cinnamon essential oil loaded by modified supercritical co(2) impregnation for long-term antibacterial packaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076511/ https://www.ncbi.nlm.nih.gov/pubmed/32085384 http://dx.doi.org/10.3390/pharmaceutics12020169 |
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