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Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines
We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for site-specific targeting of human epithelial gro...
Autores principales: | Souto, Eliana B., Souto, Selma B., Zielinska, Aleksandra, Durazzo, Alessandra, Lucarini, Massimo, Santini, Antonello, Horbańczuk, Olaf K., Atanasov, Atanas G., Marques, Conrado, Andrade, Luciana N., Silva, Amélia M., Severino, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076521/ https://www.ncbi.nlm.nih.gov/pubmed/32079103 http://dx.doi.org/10.3390/pharmaceutics12020161 |
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