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Nanoparticle-Mediated Dual Targeting: An Approach for Enhanced Baicalin Delivery to the Liver

In this study, water-soluble chitosan lactate (CL) was reacted with lactobionic acid (LA), a disaccharide with remarkable affinity to hepatic asialoglycoprotein (ASGP) receptors, to form dual liver-targeting LA-modified-CL polymer for site-specific drug delivery to the liver. The synthesized polymer...

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Detalles Bibliográficos
Autores principales: Ahmed, Iman Saad, Rashed, Hassan Medhat, Fayez, Hend, Farouk, Faten, Shamma, Rehab Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076551/
https://www.ncbi.nlm.nih.gov/pubmed/32013203
http://dx.doi.org/10.3390/pharmaceutics12020107