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Nanoparticle-Mediated Dual Targeting: An Approach for Enhanced Baicalin Delivery to the Liver
In this study, water-soluble chitosan lactate (CL) was reacted with lactobionic acid (LA), a disaccharide with remarkable affinity to hepatic asialoglycoprotein (ASGP) receptors, to form dual liver-targeting LA-modified-CL polymer for site-specific drug delivery to the liver. The synthesized polymer...
Autores principales: | Ahmed, Iman Saad, Rashed, Hassan Medhat, Fayez, Hend, Farouk, Faten, Shamma, Rehab Nabil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076551/ https://www.ncbi.nlm.nih.gov/pubmed/32013203 http://dx.doi.org/10.3390/pharmaceutics12020107 |
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