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MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles
Remyelination is a key aspect in multiple sclerosis pathology and a special effort is being made to promote it. However, there is still no available treatment to regenerate myelin and several strategies are being scrutinized. Myelination is naturally performed by oligodendrocytes and microRNAs have...
Autores principales: | Osorio-Querejeta, Iñaki, Carregal-Romero, Susana, Ayerdi-Izquierdo, Ana, Mäger, Imre, Nash, Leslie A., Wood, Matthew, Egimendia, Ander, Betanzos, M., Alberro, Ainhoa, Iparraguirre, Leire, Moles, Laura, Llarena, Irantzu, Möller, Marco, Goñi-de-Cerio, Felipe, Bijelic, Goran, Ramos-Cabrer, Pedro, Muñoz-Culla, Maider, Otaegui, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076664/ https://www.ncbi.nlm.nih.gov/pubmed/32098213 http://dx.doi.org/10.3390/pharmaceutics12020186 |
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