Chronic aerobic exercise associated to low-dose L-NAME improves contractility without changing calcium handling in rat cardiomyocytes

Nitric oxide (NO) inhibition by high-dose NG-nitro-L-arginine methyl ester (L-NAME) is associated with several detrimental effects on the cardiovascular system. However, low-dose L-NAME increases NO synthesis, which in turn induces physiological cardiovascular benefits, probably by activating a prot...

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Detalles Bibliográficos
Autores principales: Luchi, T.C., Coelho, P.M., Cordeiro, J.P., Assis, A.L.E.M., Nogueira, B.V., Marques, V.B., dos Santos, L., Lima-Leopoldo, A.P., Lunz, W., Leopoldo, A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076801/
https://www.ncbi.nlm.nih.gov/pubmed/32159612
http://dx.doi.org/10.1590/1414-431X20198761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076801/
https://www.ncbi.nlm.nih.gov/pubmed/32159612
http://dx.doi.org/10.1590/1414-431X20198761

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