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Mitochondrial dependent pathway is involved in the protective effects of carboxymethylated chitosan on nitric oxide-induced apoptosis in chondrocytes

BACKGROUND: Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodium nitroprusside (SNP)-induced chondrocyte apoptosis were evaluated and the unde...

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Detalles Bibliográficos
Autores principales: He, Bin, Wu, Fei, Li, Xiaohai, Liu, Yang, Fan, Li, Li, Haohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076817/
https://www.ncbi.nlm.nih.gov/pubmed/32020892
http://dx.doi.org/10.1186/s12906-019-2808-x