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Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
BACKGROUND: Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy bodies. Therefore, examination of compounds that abolish...
Autores principales: | Ardah, Mustafa T., Ghanem, Simona S., Abdulla, Sara A., Lv, Guohua, Emara, Mohamed M., Paleologou, Katerina E., Vaikath, Nishant N., Lu, Jia-Hong, Li, Min, Vekrellis, Konstantinos, Eliezer, David, El-Agnaf, Omar M. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076823/ https://www.ncbi.nlm.nih.gov/pubmed/32143619 http://dx.doi.org/10.1186/s12906-020-2849-1 |
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