Cargando…

Germacrone protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy processes in PC12 cells

BACKGROUND: Germacrone is an anti-inflammatory ingredient in the Chinese medicine zedoary turmeric. The purpose of this study was to explore the protective mechanism of germacrone against PC12 cells injury caused by oxygen-glucose deprivation/reperfusion (OGD/R). METHODS: OGD/R injury model of PC12...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jianxing, Yuan, Li, Wang, Sujie, Liu, Jiang, Bi, Huiqin, Chen, Guojuan, Li, Jingjing, Chen, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076837/ https://www.ncbi.nlm.nih.gov/pubmed/32145743 http://dx.doi.org/10.1186/s12906-020-2865-1

Ejemplares similares

Costunolide attenuates oxygen-glucose deprivation/reperfusion-induced mitochondrial-mediated apoptosis in PC12 cells
por: Meng, Lanqing, et al.
Publicado: (2021)

The Duration of Oxygen and Glucose Deprivation (OGD) Determines the Effects of Subsequent Reperfusion on Rat Pheochromocytoma (PC12) Cells and Primary Cortical Neurons
por: Singh, Ayesha, et al.
Publicado: (2023)

Propofol Prevents Autophagic Cell Death following Oxygen and Glucose Deprivation in PC12 Cells and Cerebral Ischemia-Reperfusion Injury in Rats
por: Cui, Derong, et al.
Publicado: (2012)

Neuroprotective Effects of Exogenous Activin A on Oxygen-Glucose Deprivation in PC12 Cells
por: He, Jin-Ting, et al.
Publicado: (2011)

Activin A prevents neuron-like PC12 cell apoptosis after oxygen-glucose deprivation☆
por: Xu, Guihua, et al.
Publicado: (2013)

Complete inhibition of phosphatase and tensin homolog promotes the normal and oxygen-glucose deprivation/reperfusion-injured PC12 cells to cell death
por: Minaei Beyrami, Sohrab, et al.
Publicado: (2018)

Retraction: Propofol Prevents Autophagic Cell Death following Oxygen and Glucose Deprivation in PC12 Cells and Cerebral Ischemia-Reperfusion Injury in Rats
Publicado: (2022)

Repeated Glucose Deprivation/Reperfusion Induced PC-12 Cell Death through the Involvement of FOXO Transcription Factor
por: Han, Na, et al.
Publicado: (2016)

Associations between Huwe1 and autophagy in rat cerebral neuron oxygen-glucose deprivation and reperfusion injury
por: He, Guo-Qian, et al.
Publicado: (2020)

Hyperbaric oxygen protects HT22 cells and PC12 cells from damage caused by oxygen-glucose deprivation/reperfusion via the inhibition of Nrf2/System Xc-/GPX4 axis-mediated ferroptosis
por: Chen, Chunxia, et al.
Publicado: (2022)

Protective effect of microRNA-340-5p against oxygen-glucose deprivation/reperfusion in PC12 cells through targeting neuronal differentiation 4
por: Wang, Juan, et al.
Publicado: (2020)

Germacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells
por: Yu, Ziqiang, et al.
Publicado: (2020)

Neuroprotective effects of leonurine against oxygen–glucose deprivation by targeting Cx36/CaMKII in PC12 cells
por: Li, Jiao, et al.
Publicado: (2018)

Glucose deprivation regulates the progranulin–sortilin axis in PC12 cells
por: Kawashima, Ken‐ichi, et al.
Publicado: (2016)

Protective Effect of Diospyros kaki against Glucose-Oxygen-Serum Deprivation-Induced PC12 Cells Injury
por: Forouzanfar, Fatemeh, et al.
Publicado: (2016)

SIRT1 Protects Against Apoptosis by Promoting Autophagy in the Oxygen Glucose Deprivation/Reperfusion-Induced Injury
por: Ren, Qiannan, et al.
Publicado: (2019)

Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway
por: Xu, Lingshan, et al.
Publicado: (2021)

Ligustilide protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced apoptosis via the LKB1-AMPK-mTOR signaling pathway
por: Zhao, Dan-Yang, et al.
Publicado: (2019)

DRAM1 Protects Neuroblastoma Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Injury via Autophagy
por: Yu, Mengqiang, et al.
Publicado: (2014)

Autophagy Induced by Oxygen-Glucose Deprivation Mediates the Injury to the Neurovascular Unit
por: Zhang, Xinyang, et al.
Publicado: (2019)

In vitro antiviral effect of germacrone on feline calicivirus
por: Wu, Hongxia, et al.
Publicado: (2016)

Neuroprotective effects of neural stem cells pretreated with neuregulin1β on PC12 cells exposed to oxygen-glucose deprivation/reoxygenation
por: Zhai, Qiu-Yue, et al.
Publicado: (2022)

Retinoic acid receptor α expression exerts an anti-apoptosis effect on PC12 cells following oxygen-glucose deprivation
por: Dong, Wanliang, et al.
Publicado: (2018)

Neuroprotective mechanism of low-dose sodium nitrite in oxygen-glucose deprivation model of cerebral ischemic stroke in PC12 cells
por: Shakib, Nader, et al.
Publicado: (2019)

Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion
por: Sun, Zuo-Yan, et al.
Publicado: (2019)

rLj-RGD3, a Novel Three-RGD-Motif-Containing Recombinant Protein from Lampetra japonica, Protects PC12 Cells from Injury Induced by Oxygen-Glucose Deprivation and Reperfusion
por: Lv, Li, et al.
Publicado: (2016)

Downregulation of MiR-218-5p Protects Against Oxygen-Glucose Deprivation/Reperfusion-Induced Injuries of PC12 Cells via Upregulating N-myc Downstream Regulated Gene 4 (NDRG4)
por: Zhu, Huiying, et al.
Publicado: (2020)

Protective Effect of Scutellaria litwinowii Extract on Serum/Glucose-Deprived Cultured PC12 Cells and Determining the Role of Reactive Oxygen Species
por: Afsharzadeh, Maryam, et al.
Publicado: (2012)

Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells
por: Liu, Liyan, et al.
Publicado: (2021)

Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro
por: He, Wanting, et al.
Publicado: (2019)

Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation
por: Pan, Tao, et al.
Publicado: (2020)

Oxygen Glucose Deprivation Induced Prosurvival Autophagy Is Insufficient to Rescue Endothelial Function
por: Natarajan, Venkateswaran, et al.
Publicado: (2020)

Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways
por: Su, Li, et al.
Publicado: (2016)

Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis
por: Tan, Tingfei, et al.
Publicado: (2022)

Proteases Inhibition Assessment on PC12 and NGF Treated Cells after Oxygen and Glucose Deprivation Reveals a Distinct Role for Aspartyl Proteases
por: Kritis, Aristidis, et al.
Publicado: (2011)

Protective effects of glucosamine and its acetylated derivative on serum/glucose deprivation-induced PC12 cells death: Role of reactive oxygen species
por: Mousavi, Seyed Hadi, et al.
Publicado: (2018)

Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion
por: He, Guo-Qian, et al.
Publicado: (2019)

The effects of icariin on the expression of HIF-1α, HSP-60 and HSP-70 in PC12 cells suffered from oxygen–glucose deprivation-induced injury
por: Mo, Zhen-Tao, et al.
Publicado: (2017)

Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway
por: Huang, Yongliang, et al.
Publicado: (2014)

Protective effect of Hibiscus sabdariffa against serum/glucose deprivation-induced PC12 cells injury
por: Bakhtiari, Elham, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dbvuupm76k05cj9fvgdjh538eq