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Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and –independent apoptosis via Smad or Akt signaling pathways in HOS cells
BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and has also been associated with a high degree of malignancy and enhanced metastatic capacity. Curcumin (CUR) is well known for its anti-osteosarcoma activity. However, both demethoxycurcumin (DMC),...
Autores principales: | Huang, Cheng, Lu, Hsu-Feng, Chen, Yu-Hsuan, Chen, Jui-Chieh, Chou, Wen-Hsiang, Huang, Hsiu-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076840/ https://www.ncbi.nlm.nih.gov/pubmed/32126993 http://dx.doi.org/10.1186/s12906-020-2857-1 |
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