Cargando…

Germacrone exerts anti-cancer effects on gastric cancer through induction of cell cycle arrest and promotion of apoptosis

BACKGROUND: Germacrone is one of the natural bioactive compounds found in Rhizoma curcuma essential oils. In this study, the potential anti-cancer effect of germacrone in gastric cancer cell line BGC823 was investigated. METHODS: The cell viability and proliferative activity were assessed, and cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Lei, Wang, Lifen, Tian, Xiangguo, Zhang, Junyong, Feng, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076853/ https://www.ncbi.nlm.nih.gov/pubmed/32020876 http://dx.doi.org/10.1186/s12906-019-2810-3

Ejemplares similares

Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells
por: Fang, Xing, et al.
Publicado: (2020)

Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway
por: Zhao, Yang, et al.
Publicado: (2021)

Germacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells
por: Yu, Ziqiang, et al.
Publicado: (2020)

Cedrus atlantica extract exerts antiproliferative effect on colorectal cancer through the induction of cell cycle arrest and apoptosis
por: Huang, Chih‐Yuan, et al.
Publicado: (2022)

Orostachys japonicus exerts antipancreatic cancer activity through induction of apoptosis and cell cycle arrest in PANC‐1 cells
por: Kim, Ji Hyun, et al.
Publicado: (2019)

Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells
por: XIE, XIAO-HONG, et al.
Publicado: (2014)

In vitro antiviral effect of germacrone on feline calicivirus
por: Wu, Hongxia, et al.
Publicado: (2016)

Lipophilized Epigallocatechin Gallate Derivative Exerts Anti-Proliferation Efficacy through Induction of Cell Cycle Arrest and Apoptosis on DU145 Human Prostate Cancer Cells
por: Chen, Jun, et al.
Publicado: (2019)

Acetyl-11-Keto-β-Boswellic Acid Exerts the Anti-Cancer Effects via Cell Cycle Arrest, Apoptosis Induction and Autophagy Suppression in Non-Small Cell Lung Cancer Cells
por: Lv, Minghe, et al.
Publicado: (2020)

Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro
por: He, Wanting, et al.
Publicado: (2019)

Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells
por: Zhang, Ren, et al.
Publicado: (2020)

Impact of Fixed-Dose Combination of Germacrone, Curdione, and Furanodiene on Breast Cancer Cell Proliferation
por: Kong, Qi, et al.
Publicado: (2013)

Apoptosis Induction, Cell Cycle Arrest and Anti-Cancer Potential of Tamoxifen-Curcumin Loaded Niosomes Against MCF-7 Cancer Cells
por: Fatemizadeh, Mahdi, et al.
Publicado: (2022)

Deoxypodophyllotoxin Exerts Anti-Cancer Effects on Colorectal Cancer Cells Through Induction of Apoptosis and Suppression of Tumorigenesis
por: Gamage, Chathurika D. B., et al.
Publicado: (2019)

Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vitro.
por: Lai, P. B., et al.
Publicado: (1996)

Suppression of oral cancer by induction of cell cycle arrest and apoptosis using Juniperus communis extract
por: Lee, Ching-Chang, et al.
Publicado: (2020)

Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells
por: Hu, Qiang, et al.
Publicado: (2017)

Cimiside E arrests cell cycle and induces cell apoptosis in gastric cancer cells
por: Guo, Lian Yu, et al.
Publicado: (2009)

Aloperine executes antitumor effects through the induction of apoptosis and cell cycle arrest in prostate cancer in vitro and in vivo
por: Ling, Zhixin, et al.
Publicado: (2018)

Cellular Effect of Curcumin and Citral Combination on Breast Cancer Cells: Induction of Apoptosis and Cell Cycle Arrest
por: Patel, Pinaki B., et al.
Publicado: (2015)

Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest
por: Oak, Christine, et al.
Publicado: (2018)

Selenium speciation-dependent cancer radiosensitization by induction of G2/M cell cycle arrest and apoptosis
por: Nie, Shiqing, et al.
Publicado: (2023)

Chlorogenic Acid and Its Microbial Metabolites Exert Anti-Proliferative Effects, S-Phase Cell-Cycle Arrest and Apoptosis in Human Colon Cancer Caco-2 Cells
por: Sadeghi Ekbatan, Shima, et al.
Publicado: (2018)

Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells
por: Liu, Xinghua, et al.
Publicado: (2012)

A Novel Tanshinone Analog Exerts Anti-Cancer Effects in Prostate Cancer by Inducing Cell Apoptosis, Arresting Cell Cycle at G2 Phase and Blocking Metastatic Ability
por: Wang, Mengling, et al.
Publicado: (2019)

Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo
por: Geng, Xiaoge, et al.
Publicado: (2018)

Glycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis
por: Wang, Hao, et al.
Publicado: (2020)

Induction of Apoptosis and Cell Cycle Arrest by Dorema Glabrum Root Extracts in a Gastric Adenocarcinoma (AGS) Cell Line
por: Jafari, Naser, et al.
Publicado: (2016)

Bergamottin exerts anticancer effects on human colon cancer cells via induction of apoptosis, G2/M cell cycle arrest and deactivation of the Ras/Raf/ERK signalling pathway
por: Zhang, Hao, et al.
Publicado: (2019)

Apoptosis Induction, a Sharp Edge of Berberine to Exert Anti-Cancer Effects, Focus on Breast, Lung, and Liver Cancer
por: Zhu, Yi, et al.
Publicado: (2022)

Germacrone Derivatives as new Insecticidal and Acaricidal Compounds: A Structure-Activity Relationship
por: Galisteo Pretel, Alberto, et al.
Publicado: (2019)

Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction
por: Zhao, Fuguang, et al.
Publicado: (2020)

Induction of apoptosis and cell cycle arrest in colorectal cancer cells by novel anticancer metabolites of Streptomyces sp. 801
por: Kouroshnia, Arghavan, et al.
Publicado: (2022)

In Vitro Antiproliferative Apoptosis Induction and Cell Cycle Arrest Potential of Saudi Sidr Honey against Colorectal Cancer
por: Qanash, Husam, et al.
Publicado: (2023)

Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach
por: Kong, Qi, et al.
Publicado: (2017)

ZHX1 Inhibits Gastric Cancer Cell Growth through Inducing Cell-Cycle Arrest and Apoptosis
por: Ma, Xingjie, et al.
Publicado: (2016)

Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
por: Zhang, Xin, et al.
Publicado: (2019)

Chinese Propolis Inhibits the Proliferation of Human Gastric Cancer Cells by Inducing Apoptosis and Cell Cycle Arrest
por: Jiang, Xia-sen, et al.
Publicado: (2020)

Daidzein exerts anticancer activity towards SKOV3 human ovarian cancer cells by inducing apoptosis and cell cycle arrest, and inhibiting the Raf/MEK/ERK cascade
por: Hua, Fu, et al.
Publicado: (2021)

Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis
por: Razak, Nursyamirah Abd, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hlcie7gd10hgbkve2s4n1dq3c2