Cargando…

Mechanism of tanshinones and phenolic acids from Danshen in the treatment of coronary heart disease based on co-expression network

BACKGROUND: The tanshinones and phenolic acids in Salvia miltiorrhiza (also named Danshen) have been confirmed for the treatment of coronary heart disease (CHD), but the action mechanisms remain elusive. METHODS: In the current study, the co-expression protein interaction network (Ce-PIN) was used t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Dongxue, Huo, Mengqi, Chen, Xi, Zhang, Yanling, Qiao, Yanjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076864/ https://www.ncbi.nlm.nih.gov/pubmed/32020855 http://dx.doi.org/10.1186/s12906-019-2712-4

Ejemplares similares

Using Coexpression Protein Interaction Network Analysis to Identify Mechanisms of Danshensu Affecting Patients with Coronary Heart Disease
por: Huo, Mengqi, et al.
Publicado: (2017)

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA
por: Shen, Jui-Lung, et al.
Publicado: (2011)

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)
por: Naz, Irum, et al.
Publicado: (2020)

Simultaneous Determination of Eight Phenolic Acids, Five Saponins and Four Tanshinones for Quality Control of Compound Preparations Containing Danshen-Sanqi Herb-pair by HPLC-DAD
por: Yao, Hong, et al.
Publicado: (2017)

Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia
por: Lee, Jae-Chul, et al.
Publicado: (2013)

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
por: Ma, Xiao-Hui, et al.
Publicado: (2015)

Tanshinones and diethyl blechnics with anti-inflammatory and anti-cancer activities from Salvia miltiorrhiza Bunge (Danshen)
por: Gao, Hongwei, et al.
Publicado: (2016)

A Review of Danshen Combined with Clopidogrel in the Treatment of Coronary Heart Disease
por: Zhang, Zhaojian, et al.
Publicado: (2019)

Molecular Basis Underlying Hepatobiliary and Renal Excretion of Phenolic Acids of Salvia miltiorrhiza Roots (Danshen)
por: Lu, Jun-Lan, et al.
Publicado: (2022)

Rapid Characterization of Tanshinone Extract Powder by Near Infrared Spectroscopy
por: Luo, Gan, et al.
Publicado: (2015)

A Pair of New Antioxidant Phenolic Acid Stereoisomers Isolated from Danshen Injection (Lyophilized Powder)
por: Liu, Jing, et al.
Publicado: (2014)

A Discovery Strategy for Active Compounds of Chinese Medicine Based on the Prediction Model of Compound-Disease Relationship
por: Huo, Mengqi, et al.
Publicado: (2022)

The anticancer mechanism investigation of Tanshinone II(A) by pharmacological clustering in protein network
por: Cao, Yan-feng, et al.
Publicado: (2018)

The Efficacy and Safety of Compound Danshen Dripping Pill Combined with Percutaneous Coronary Intervention for Coronary Heart Disease
por: Li, Cailan, et al.
Publicado: (2020)

Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease
por: Liu, Boyan, et al.
Publicado: (2016)

The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis
por: Zheng, Shichao, et al.
Publicado: (2015)

Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
por: Li, Jie, et al.
Publicado: (2018)

Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-κB Pathway
por: Hou, Jingyi, et al.
Publicado: (2018)

Correction: Hou, J., et al. Anti-Inflammatory Effects of Aurantio-Obstusin From Seed of Cassia obtusifolia L. Through Modulation of the NF-κB Pathway. Molecules 2018, 23, 3093
por: Hou, Jingyi, et al.
Publicado: (2019)

Comprehensive transcriptome profiling of Salvia miltiorrhiza for discovery of genes associated with the biosynthesis of tanshinones and phenolic acids
por: Zhou, Wei, et al.
Publicado: (2017)

Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions
por: Tung, Yu-Tang, et al.
Publicado: (2013)

Effect of various Danshen injections on patients with coronary heart disease after percutaneous coronary intervention: A protocol for a systematic review and network meta-analysis
por: Zhu, Zehao, et al.
Publicado: (2018)

Compound Danshen dripping pills in treating with coronary heart disease: A protocol for systematic review and meta-analysis
por: Sun, Ling, et al.
Publicado: (2022)

Diterpenoid Tanshinones and Phenolic Acids from Cultured Hairy Roots of Salvia miltiorrhiza Bunge and Their Antimicrobial Activities
por: Zhao, Jianglin, et al.
Publicado: (2011)

SmGRAS1 and SmGRAS2 Regulate the Biosynthesis of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
por: Li, Wenrui, et al.
Publicado: (2019)

The mechanisms of tanshinone in the treatment of tumors
por: Zhang, Pengyu, et al.
Publicado: (2023)

Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling
por: Dou, Jing-Yun, et al.
Publicado: (2022)

Mechanisms and Molecular Targets of Compound Danshen Dropping Pill for Heart Disease Caused by High Altitude Based on Network Pharmacology and Molecular Docking
por: Yan, Jiayi, et al.
Publicado: (2021)

Beneficial effects of endophytic fungi inoculation on tanshinones and phenolic compounds of Salvia abrotanoides
por: Masoudi Khorasani, Fatemeh, et al.
Publicado: (2023)

Transcriptional Profiles of SmWRKY Family Genes and Their Putative Roles in the Biosynthesis of Tanshinone and Phenolic Acids in Salvia miltiorrhiza
por: Yu, Haizheng, et al.
Publicado: (2018)

Ag(+) as a More Effective Elicitor for Production of Tanshinones than Phenolic Acids in Salvia miltiorrhiza Hairy Roots
por: Xing, Bingcong, et al.
Publicado: (2014)

The Clinical Pharmacokinetics and Pharmacodynamics of Warfarin When Combined with Compound Danshen: A Case Study for Combined Treatment of Coronary Heart Diseases with Atrial Fibrillation
por: Lv, Chunxiao, et al.
Publicado: (2017)

A bioinformatics investigation into the pharmacological mechanisms of the effect of Fufang Danshen on pain based on methodologies of network pharmacology
por: Sun, Yantao, et al.
Publicado: (2019)

Exploration on Molecular Mechanism of Reversal Effect of Compound Danshen Tablets on Hepatic Fibrosis Based on Network Pharmacology
por: Cao, Minling, et al.
Publicado: (2022)

bHLH transcription factor SmbHLH92 negatively regulates biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza
por: Zhang, Jian-hong, et al.
Publicado: (2020)

Proangiogenesis effects of compound danshen dripping pills in zebrafish
por: Hu, Yang-Xi, et al.
Publicado: (2022)

Functional pleiotropism, diversity, and redundancy of Salvia miltiorrhiza Bunge JAZ family proteins in jasmonate-induced tanshinone and phenolic acid biosynthesis
por: Ma, Pengda, et al.
Publicado: (2022)

Using network pharmacology and molecular docking to explore the underlying anti-inflammatory mechanism of Wuyao-Danshen to treat endometriosis
por: Zhu, Jie, et al.
Publicado: (2022)

Study on the mechanism of Danshen-Guizhi drug pair in the treatment of ovarian cancer based on network pharmacology and in vitro experiment
por: Qin, Chongzhen, et al.
Publicado: (2022)

Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy
por: Liu, Mengnan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_avn98gmah0vbooh7j7cbbpfnc2