Cargando…

Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract

BACKGROUND: The well-known traditional Chinese herbal formula Guizhi Fuling Wan (GFW) was recently reported to improve the curative effects of chemotherapy for ovarian cancer with few clinical side effects. The present study aimed to investigate the reversal mechanism of sera derived from rats expos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Li, Cao, Xueyun, Chen, Zhong, Guo, Xiaojuan, Yang, Lei, Zhou, Yubing, Bian, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076886/ https://www.ncbi.nlm.nih.gov/pubmed/32066429 http://dx.doi.org/10.1186/s12906-020-2825-9

Ejemplares similares

Guizhi Fuling Wan, a Traditional Chinese Herbal Formula, Sensitizes Cisplatin-Resistant Human Ovarian Cancer Cells through Inactivation of the PI3K/AKT/mTOR Pathway
por: Han, Li, et al.
Publicado: (2016)

Efficacy of Guizhi Fuling Wan for primary dysmenorrhea: protocol for a randomized controlled trial
por: Du, Yun, et al.
Publicado: (2021)

A network pharmacology approach to investigate the pharmacological effects of Guizhi Fuling Wan on uterine fibroids
por: Zeng, Liuting, et al.
Publicado: (2017)

Integrating Network Pharmacology and Experimental Validation Deciphers the Mechanism of Guizhi Fuling Wan against Adenomyosis
por: Wang, Haoxian, et al.
Publicado: (2021)

Correction to: Efficacy of Guizhi Fuling Wan for primary dysmenorrhea: protocol for a randomized controlled trial
por: Du, Yun, et al.
Publicado: (2021)

Utilizing network pharmacology and molecular docking to explore the underlying mechanism of Guizhi Fuling Wan in treating endometriosis
por: Wang, Haoxian, et al.
Publicado: (2021)

Guizhi Fuling wan for chronic pelvic inflammatory disease protocol: A protocol for systematic review and meta analysis
por: Wang, Chunrong, et al.
Publicado: (2020)

The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder
por: Lu, Chi-Chen, et al.
Publicado: (2013)

A Classic Herbal Formula Guizhi Fuling Wan for Menopausal Hot Flushes: From Experimental Findings to Clinical Applications
por: Li, Mingdi, et al.
Publicado: (2019)

Analysis of the Mechanism of GuizhiFuling Wan in Treating Adenomyosis Based on Network Pharmacology Combined with Molecular Docking and Experimental Verification
por: Shi, Yaxin, et al.
Publicado: (2022)

High-throughput metabolomics used to identify potential therapeutic targets of Guizhi Fuling Wan against endometriosis of cold coagulation and blood stasis
por: Wu, Xiu-hong, et al.
Publicado: (2018)

The Multiple Pharmacologic Functions and Mechanisms of Action of Guizhi Fuling Formulation
por: Gao, Jie, et al.
Publicado: (2022)

Guizhi Fuling Wan, Chinese Herbal Medicine, Ameliorates Insulin Sensitivity in PCOS Model Rats With Insulin Resistance via Remodeling Intestinal Homeostasis
por: Zhu, Ying, et al.
Publicado: (2020)

Guizhi Fuling Capsule Exhibits Antidysmenorrhea Activity by Inhibition of Cyclooxygenase Activity
por: Zheng, Weiran, et al.
Publicado: (2020)

Metabolomics Study of Guizhi Fuling Capsules in Rats With Cold Coagulation Dysmenorrhea
por: Zhang, Yu, et al.
Publicado: (2021)

Traditional Chinese medicine prescription Guizhi Fuling Pills in the treatment of endometriosis
por: Wang, Xin, et al.
Publicado: (2021)

A Novel Method HPLC-DAD Analysis of the Contentsof Moutan Cortexand Paeoniae Radix Alba with Similar Constituents-Monoterpene Glycosides in Guizhi Fuling Wan
por: Wang, Shuyun, et al.
Publicado: (2014)

Efficacy of different forms of Guizhi Fuling Wan on reproduction and metabolism in women with polycystic ovary syndrome: A protocol for a meta-analysis of randomized controlled trials
por: Liu, Min, et al.
Publicado: (2020)

The Effects of Guizhi Fuling Capsule Drug Serum on Uterine Leiomyoma Cells and Its Mechanism
por: Shen, Qi, et al.
Publicado: (2016)

Deciphering the Pharmacological Mechanisms of Guizhi-Fuling Capsule on Primary Dysmenorrhea Through Network Pharmacology
por: Zhang, Siqin, et al.
Publicado: (2021)

Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers
por: Zhong, Yun-Xi, et al.
Publicado: (2016)

PB2076: GUIZHI FULING CAPSULE REGULATES AUTOPHAGY TO INTERFERE WITH BORTEZOMIB-INDUCED PERIPHERAL NEUROPATHY
por: Fu, Jiaqi, et al.
Publicado: (2023)

Add-on effect of Guizhi Fuling formula to mifepristone for endometriosis: A meta-analysis of randomized controlled trials
por: Meng, Wenbin, et al.
Publicado: (2019)

Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Duan, Bailu, et al.
Publicado: (2020)

Research on Quality Markers of Guizhi Fuling Prescription for Endometriosis Treatment Based on Gray Correlation Analysis Strategy
por: Chen, Jinpeng, et al.
Publicado: (2021)

Guizhi-Fuling-Wan, a Traditional Chinese Herbal Medicine, Ameliorates Memory Deficits and Neuronal Apoptosis in the Streptozotocin-Induced Hyperglycemic Rodents via the Decrease of Bax/Bcl2 Ratio and Caspase-3 Expression
por: Wu, Kuo-Jen, et al.
Publicado: (2012)

Chinese herbal medicine Guizhi Fuling Formula for treatment of uterine fibroids: a systematic review of randomised clinical trials
por: Chen, Ni-Ni, et al.
Publicado: (2014)

Evaluation of Anti-Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells
por: Zheng, Yuzhong, et al.
Publicado: (2020)

Invasiveness of endometrial cancer cell lines is potentiated by estradiol and blocked by a traditional medicine Guizhi Fuling at clinically relevant doses
por: Khan, Sidra, et al.
Publicado: (2023)

Guizhi Fuling Decoction inhibiting the PI3K and MAPK pathways in breast cancer cells revealed by HTS(2) technology and systems pharmacology
por: Dai, Yifei, et al.
Publicado: (2020)

Add-on effect of the Guizhi Fuling formula for management of reduced fertility potential in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials
por: Rong, Anna, et al.
Publicado: (2023)

Neuroprotection of Gueichih-Fuling-Wan on cerebral ischemia/ reperfusion injury in streptozotocin-induced hyperglycemic rats via the inhibition of the cellular apoptosis pathway and neuroinflammation
por: Chen, Yuh-Fung, et al.
Publicado: (2016)

The MTDH (−470G>A) Polymorphism Is Associated with Ovarian Cancer Susceptibility
por: Yuan, Cunzhong, et al.
Publicado: (2012)

Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways
por: Liu, Zhongliang, et al.
Publicado: (2022)

Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice
por: Yang, Guang, et al.
Publicado: (2023)

MicroRNA-98/PTEN/AKT pathway inhibits cell proliferation and malignant progression of hypopharyngeal carcinoma by MTDH
por: Wang, Qiwei, et al.
Publicado: (2019)

The efficacy and safety of Chinese herbal medicine Guizhi Fuling capsule combined with low dose mifepristone in the treatment of uterine fibroids: a systematic review and meta-analysis of 28 randomized controlled trials
por: Lei, Yiming, et al.
Publicado: (2023)

microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway
por: Zhang, Lunqiang, et al.
Publicado: (2019)

miRNA-559 and MTDH as possible diagnostic markers of psoriasis: Role of PTEN/AKT/FOXO pathway in disease pathogenesis
por: Aldabbas, Rana, et al.
Publicado: (2022)

microRNA-877 Inhibits Malignant Progression of Colorectal Cancer by Directly Targeting MTDH and Regulating the PTEN/Akt Pathway [Retraction]
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a514to3mh3jps86thi6tiel9ik