Cargando…

Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis

BACKGROUND: Osteoporosis is related to the number and activity of osteoclasts. The goal of the present study was to demonstrate the effect of Chaenomelis Fructus (CF) on osteoclastogenesis and its mechanism of bone loss prevention in an OVX-induced osteoporosis model. METHODS: Osteoclasts were induc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Minsun, Kim, Ho-Seok, Kim, Jae-Hyun, Kim, Eun-Young, Lee, Bina, Lee, Sung Yub, Jun, Jae-Yun, Kim, Min Beom, Sohn, Youngjoo, Jung, Hyuk-Sang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076887/ https://www.ncbi.nlm.nih.gov/pubmed/32024503 http://dx.doi.org/10.1186/s12906-020-2841-9

Ejemplares similares

Gleditsiae fructus regulates osteoclastogenesis by inhibiting the c‑Fos/NFATc1 pathway and alleviating bone loss in an ovariectomy model
por: Cho, Chang-Young, et al.
Publicado: (2023)

Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy-induced osteoporosis model
por: Kim, Jae-Hyun, et al.
Publicado: (2021)

A HPLC fingerprint study on Chaenomelis Fructus
por: Zhu, Lili, et al.
Publicado: (2019)

Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation
por: Kim, Jae-Hyun, et al.
Publicado: (2019)

Effects of Sparganii Rhizoma on Osteoclast Formation and Osteoblast Differentiation and on an OVX-Induced Bone Loss Model
por: Lee, Sungyub, et al.
Publicado: (2022)

Isovaleric acid ameliorates ovariectomy‐induced osteoporosis by inhibiting osteoclast differentiation
por: Cho, Kwang Min, et al.
Publicado: (2021)

Effects of Melandrium firmum Rohrbach on RANKL-induced osteoclast differentiation and OVX rats
por: Kim, Minsun, et al.
Publicado: (2021)

Xanthii Fructus inhibits allergic response in the ovalbumin-sensitized mouse allergic rhinitis model
por: Gwak, Nam-Gil, et al.
Publicado: (2015)

Exploring the Anti-Osteoporotic Potential of Daucosterol: Impact on Osteoclast and Osteoblast Activities
por: Lee, Sumin, et al.
Publicado: (2023)

Crataegus pinnatifida Bunge Inhibits RANKL-Induced Osteoclast Differentiation in RAW 264.7 Cells and Prevents Bone Loss in an Ovariectomized Rat Model
por: Kim, Minsun, et al.
Publicado: (2021)

Rapid determination of the total content of oleanolic acid and ursolic acid in Chaenomelis Fructus using near-infrared spectroscopy
por: Ming, Jing, et al.
Publicado: (2022)

Regulation of NFATc1 in Osteoclast Differentiation
por: Kim, Jung Ha, et al.
Publicado: (2014)

Effect of Taraxaci Herba on Bone Loss in an OVX-Induced Model through the Regulation of Osteoclast Differentiation
por: Heo, Jun, et al.
Publicado: (2022)

Betulin Suppresses Osteoclast Formation via Down-Regulating NFATc1
por: Kim, Kwang-Jin, et al.
Publicado: (2018)

Water extract of Cnidii Rhizoma suppresses RANKL-induced osteoclastogenesis in RAW 264.7 cell by inhibiting NFATc1/c-Fos signaling and prevents ovariectomized bone loss in SD-rat
por: Lee, Ka-Yeon, et al.
Publicado: (2019)

Dolichos Lablab Linné Inhibits Bone Density Loss and Promotes Bone Union in Senile Osteoporosis through Osteogenesis
por: Kim, Minsun, et al.
Publicado: (2023)

Lycii radicis cortex inhibits glucocorticoid-induced bone loss by downregulating Runx2 and BMP-2 expression
por: Lee, Bina, et al.
Publicado: (2021)

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis
por: Tzeng, Huey-En, et al.
Publicado: (2018)

Sphingosylphosphorylcholine blocks ovariectomy‐induced bone loss by suppressing Ca(2+)/calmodulin‐mediated osteoclast differentiation
por: Lee, Ha Young, et al.
Publicado: (2020)

Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy
por: Lee, Hye-Hwa, et al.
Publicado: (2020)

Solanum nigrum Linne improves DNCB-induced atopic dermatitis-like skin disease in BALB/c mice
por: Hong, Sooyeon, et al.
Publicado: (2020)

Zinc inhibits osteoclast differentiation by suppression of Ca(2+)-Calcineurin-NFATc1 signaling pathway
por: Park, Kwang Hwan, et al.
Publicado: (2013)

The effects of Lycii Radicis Cortex on RANKL-induced osteoclast differentiation and activation in RAW 264.7 cells
por: KIM, JAE-HYUN, et al.
Publicado: (2016)

Protective Effect of Ciclopirox against Ovariectomy-Induced Bone Loss in Mice by Suppressing Osteoclast Formation and Function
por: Ihn, Hye Jung, et al.
Publicado: (2021)

Protective Effects of Melon Extracts on Bone Strength, Mineralization, and Metabolism in Rats with Ovariectomy-Induced Osteoporosis
por: Kim, Bongju, et al.
Publicado: (2019)

Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells
por: Kim, Jeong-Mi, et al.
Publicado: (2017)

1,3-Dibenzyl-5-Fluorouracil Prevents Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Differentiation
por: Jeon, Hyoeun, et al.
Publicado: (2022)

Erratum to: Sophorae Flos extract inhibits RANKL-induced osteoclast differentiation by suppressing the NF-κB/NFATc1 pathway in mouse bone marrow cells
por: Kim, Jeong-Mi, et al.
Publicado: (2017)

Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling
por: Kim, Jae-Hyun, et al.
Publicado: (2021)

The Brown Algae Ishige sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis through Downregulation of NFATc1/c-Fos
por: Kim, Mihyang, et al.
Publicado: (2022)

Antiosteoclastic Activity of Milk Thistle Extract after Ovariectomy to Suppress Estrogen Deficiency-Induced Osteoporosis
por: Kim, Jung-Lye, et al.
Publicado: (2013)

IRF2 enhances RANKL-induced osteoclast differentiation via regulating NF-κB/NFATc1 signaling
por: Kim, Inyoung, et al.
Publicado: (2021)

Tusc2/Fus1 regulates osteoclast differentiation through NF-κB and NFATc1
por: Kim, Inyoung, et al.
Publicado: (2017)

Inhibitory Effect of Purpurogallin on Osteoclast Differentiation In Vitro through the Downregulation of c-Fos and NFATc1
por: Kim, Kiryeong, et al.
Publicado: (2018)

Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression
por: Kim, Eun-Jung, et al.
Publicado: (2018)

Rhus javanica Gall Extract Inhibits the Differentiation of Bone Marrow-Derived Osteoclasts and Ovariectomy-Induced Bone Loss
por: Kim, Tae-Ho, et al.
Publicado: (2016)

Ethanol Extract of Radix Asteris Suppresses Osteoclast Differentiation and Alleviates Osteoporosis
por: Lee, Sung-Ju, et al.
Publicado: (2023)

Effect of Cone of Pinus densiflora on DNCB-Induced Allergic Contact Dermatitis-Like Skin Lesion in Balb/c Mice
por: Kwon, Boguen, et al.
Publicado: (2021)

AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells
por: Im, Jin Young, et al.
Publicado: (2014)

Persicae Semen Promotes Bone Union in Rat Fractures by Stimulating Osteoblastogenesis through BMP-2 and Wnt Signaling
por: Jun, Jae-Yun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_shi4qa1v749i4hoq41i4vnrvjf