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Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells
BACKGROUND: Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are urgently required for patients with drug-resistant BL. To investigate the mechan...
Autores principales: | Tabata, Mitsuki, Tsubaki, Masanobu, Takeda, Tomoya, Tateishi, Keisuke, Tsurushima, Katsumasa, Imano, Motohiro, Satou, Takao, Ishizaka, Toshihiko, Nishida, Shozo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076888/ https://www.ncbi.nlm.nih.gov/pubmed/32171300 http://dx.doi.org/10.1186/s12906-020-2879-8 |
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