Cargando…

Isoniazid causes heart looping disorder in zebrafish embryos by the induction of oxidative stress

BACKGROUND: The cardiotoxicity of isoniazid on zebrafish embryos and its underlying mechanism is unclear. METHODS: Here, we exposed zebrafish embryos at 4 h post-fertilization to different levels of isoniazid and recorded the morphology and number of malformed and dead embryos under the microscope....

Descripción completa

Detalles Bibliográficos
Autores principales: Ni, Jie, Wang, Hongye, Wei, Xiyi, Shen, Kangjie, Sha, Yeqin, Dong, Yuxiang, Shu, Yimei, Wan, Xiaojie, Cheng, Jingwen, Wang, Fang, Liu, Yihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076990/
https://www.ncbi.nlm.nih.gov/pubmed/32178728
http://dx.doi.org/10.1186/s40360-020-0399-2