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Isoniazid causes heart looping disorder in zebrafish embryos by the induction of oxidative stress

BACKGROUND: The cardiotoxicity of isoniazid on zebrafish embryos and its underlying mechanism is unclear. METHODS: Here, we exposed zebrafish embryos at 4 h post-fertilization to different levels of isoniazid and recorded the morphology and number of malformed and dead embryos under the microscope....

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Detalles Bibliográficos
Autores principales:	Ni, Jie, Wang, Hongye, Wei, Xiyi, Shen, Kangjie, Sha, Yeqin, Dong, Yuxiang, Shu, Yimei, Wan, Xiaojie, Cheng, Jingwen, Wang, Fang, Liu, Yihai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076990/ https://www.ncbi.nlm.nih.gov/pubmed/32178728 http://dx.doi.org/10.1186/s40360-020-0399-2

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