Variant effect predictions capture some aspects of deep mutational scanning experiments

BACKGROUND: Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – missense SNV...

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Detalles Bibliográficos
Autores principales: Reeb, Jonas, Wirth, Theresa, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077003/
https://www.ncbi.nlm.nih.gov/pubmed/32183714
http://dx.doi.org/10.1186/s12859-020-3439-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077003/
https://www.ncbi.nlm.nih.gov/pubmed/32183714
http://dx.doi.org/10.1186/s12859-020-3439-4

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