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Variant effect predictions capture some aspects of deep mutational scanning experiments
BACKGROUND: Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – missense SNV...
Autores principales: | Reeb, Jonas, Wirth, Theresa, Rost, Burkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077003/ https://www.ncbi.nlm.nih.gov/pubmed/32183714 http://dx.doi.org/10.1186/s12859-020-3439-4 |
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