Cisplatin Resistance in Osteosarcoma: In vitro Validation of Candidate DNA Repair-Related Therapeutic Targets and Drugs for Tailored Treatments

Treatment of high-grade osteosarcoma, the most common malignant tumor of bone, is largely based on administration of cisplatin and other DNA damaging drugs. Altered DNA repair mechanisms may thus significantly impact on either response or resistance to chemotherapy. In this study, by using a panel o...

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Detalles Bibliográficos
Autores principales: Fanelli, Marilù, Tavanti, Elisa, Patrizio, Maria Pia, Vella, Serena, Fernandez-Ramos, Amira, Magagnoli, Federica, Luppi, Silvia, Hattinger, Claudia Maria, Serra, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077033/
https://www.ncbi.nlm.nih.gov/pubmed/32211337
http://dx.doi.org/10.3389/fonc.2020.00331

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