Oxidative Stress in Canine Histiocytic Sarcoma Cells Induced by an Infection with Canine Distemper Virus Led to a Dysregulation of HIF-1α Downstream Pathway Resulting in a Reduced Expression of VEGF-B In Vitro

Histiocytic sarcomas represent malignant tumors which require new treatment strategies. Canine distemper virus (CDV) is a promising candidate due to its oncolytic features reported in a canine histiocytic sarcoma cell line (DH82 cells). Interestingly, the underlying mechanism might include a dysregu...

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Detalles Bibliográficos
Autores principales: Armando, Federico, Gambini, Matteo, Corradi, Attilio, Giudice, Chiara, Pfankuche, Vanessa Maria, Brogden, Graham, Attig, Friederike, von Köckritz-Blickwede, Maren, Baumgärtner, Wolfgang, Puff, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077254/
https://www.ncbi.nlm.nih.gov/pubmed/32054075
http://dx.doi.org/10.3390/v12020200

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