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TSPphg Lysin from the Extremophilic Thermus Bacteriophage TSP4 as a Potential Antimicrobial Agent against Both Gram-Negative and Gram-Positive Pathogenic Bacteria
New strategies against antibiotic-resistant bacterial pathogens are urgently needed but are not within reach. Here, we present in vitro and in vivo antimicrobial activity of TSPphg, a novel phage lysin identified from extremophilic Thermus phage TSP4 by sequencing its whole genome. By breaking down...
Autores principales: | Wang, Feng, Ji, Xinyu, Li, Qiupeng, Zhang, Guanling, Peng, Jiani, Hai, Jun, Zhang, Yao, Ci, Baiquan, Li, Hongwei, Xiong, Yan, Deng, Xianyu, Lin, Lianbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077265/ https://www.ncbi.nlm.nih.gov/pubmed/32050494 http://dx.doi.org/10.3390/v12020192 |
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