Cargando…
Development of Antibodies with Broad Neutralization Specificities against HIV-1 after Long Term SHIV Infection in Macaques
Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutralizing antibodies (bnAbs) develop in NHPs. To addres...
Autores principales: | Gao, Nan, Gai, Yanxin, Meng, Lina, Wang, Chu, Zhang, Xin, Wang, Wei, Qin, Chuan, Yu, Xianghui, Gao, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077270/ https://www.ncbi.nlm.nih.gov/pubmed/32023860 http://dx.doi.org/10.3390/v12020163 |
Ejemplares similares
-
Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
por: Wen, Jing, et al.
Publicado: (2021) -
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
por: Shingai, Masashi, et al.
Publicado: (2014) -
Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
por: Hora, Bhavna, et al.
Publicado: (2023) -
Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques
por: Rosenberg, Yvonne J., et al.
Publicado: (2016) -
Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure
por: Suphaphiphat, Karunasinee, et al.
Publicado: (2023)