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Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077356/ https://www.ncbi.nlm.nih.gov/pubmed/32256246 http://dx.doi.org/10.1080/01621459.2018.1469994 |
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author | Rubin-Delanchy, Patrick Heard, Nicholas A. Lawson, Daniel J. |
author_facet | Rubin-Delanchy, Patrick Heard, Nicholas A. Lawson, Daniel J. |
author_sort | Rubin-Delanchy, Patrick |
collection | PubMed |
description | The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application. |
format | Online Article Text |
id | pubmed-7077356 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-70773562020-03-30 Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order Rubin-Delanchy, Patrick Heard, Nicholas A. Lawson, Daniel J. J Am Stat Assoc Theory and Methods The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application. Taylor & Francis 2018-08-06 /pmc/articles/PMC7077356/ /pubmed/32256246 http://dx.doi.org/10.1080/01621459.2018.1469994 Text en © 2018 The Authors. Published with license by Taylor and Francis This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Theory and Methods Rubin-Delanchy, Patrick Heard, Nicholas A. Lawson, Daniel J. Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title | Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title_full | Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title_fullStr | Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title_full_unstemmed | Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title_short | Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order |
title_sort | meta-analysis of mid-p-values: some new results based on the convex order |
topic | Theory and Methods |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077356/ https://www.ncbi.nlm.nih.gov/pubmed/32256246 http://dx.doi.org/10.1080/01621459.2018.1469994 |
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