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Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order

The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual...

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Autores principales: Rubin-Delanchy, Patrick, Heard, Nicholas A., Lawson, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077356/
https://www.ncbi.nlm.nih.gov/pubmed/32256246
http://dx.doi.org/10.1080/01621459.2018.1469994
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author Rubin-Delanchy, Patrick
Heard, Nicholas A.
Lawson, Daniel J.
author_facet Rubin-Delanchy, Patrick
Heard, Nicholas A.
Lawson, Daniel J.
author_sort Rubin-Delanchy, Patrick
collection PubMed
description The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application.
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spelling pubmed-70773562020-03-30 Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order Rubin-Delanchy, Patrick Heard, Nicholas A. Lawson, Daniel J. J Am Stat Assoc Theory and Methods The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application. Taylor & Francis 2018-08-06 /pmc/articles/PMC7077356/ /pubmed/32256246 http://dx.doi.org/10.1080/01621459.2018.1469994 Text en © 2018 The Authors. Published with license by Taylor and Francis This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Theory and Methods
Rubin-Delanchy, Patrick
Heard, Nicholas A.
Lawson, Daniel J.
Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title_full Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title_fullStr Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title_full_unstemmed Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title_short Meta-Analysis of Mid-p-Values: Some New Results based on the Convex Order
title_sort meta-analysis of mid-p-values: some new results based on the convex order
topic Theory and Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077356/
https://www.ncbi.nlm.nih.gov/pubmed/32256246
http://dx.doi.org/10.1080/01621459.2018.1469994
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