Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC

[Cu(ttpy‐tpp)Br(2)]Br (abbreviated as CTB) is a novel mitochondrion‐targeting copper(II) complex synthesized by our research group, which contains tri‐phenyl‐phosphonium (TPP) groups as its lipophilic property. In this study, we explored how CTB affects mitochondrial functions and exerts its anti‐tu...

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Detalles Bibliográficos
Autores principales: Li, Mengmeng, Shao, Jiangjuan, Guo, Zijian, Jin, Chun, Wang, Ling, Wang, Feixia, Jia, Yan, Zhu, Zhenzhu, Zhang, Ziji, Zhang, Feng, Zheng, Shizhong, Wang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077532/
https://www.ncbi.nlm.nih.gov/pubmed/31994339
http://dx.doi.org/10.1111/jcmm.14971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077532/
https://www.ncbi.nlm.nih.gov/pubmed/31994339
http://dx.doi.org/10.1111/jcmm.14971

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