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Metformin upregulates mitophagy in patients with T2DM: A randomized placebo‐controlled study
Impaired mitochondrial autophagy (mitophagy) and NLRP3 inflammasome activation have been incriminated in the pathogenesis of T2DM. Metformin besides being an insulin sensitizer also induces autophagy; however, its effect on mitophagy and NLRP3 activation in patients with T2DM still remains elusive....
Autores principales: | Bhansali, Shipra, Bhansali, Anil, Dutta, Pinaki, Walia, Rama, Dhawan, Veena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077543/ https://www.ncbi.nlm.nih.gov/pubmed/31975558 http://dx.doi.org/10.1111/jcmm.14834 |
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