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HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
OBJECTIVE: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. METHODS: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade de Pediatria de São Paulo
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077793/ https://www.ncbi.nlm.nih.gov/pubmed/32187303 http://dx.doi.org/10.1590/1984-0462/2020/38/2019073 |
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author | Silva, Lílian Caroline de Souza e Silva, Skalyt Lee Barbosa e de Oliveira, Ávilla Monalisa Silva de Araujo, Jacqueline Rosangela de Arruda, Ilma Kruze Grande Maio, Regiane de Lemos, Maria da Conceição Chaves |
author_facet | Silva, Lílian Caroline de Souza e Silva, Skalyt Lee Barbosa e de Oliveira, Ávilla Monalisa Silva de Araujo, Jacqueline Rosangela de Arruda, Ilma Kruze Grande Maio, Regiane de Lemos, Maria da Conceição Chaves |
author_sort | Silva, Lílian Caroline de Souza e |
collection | PubMed |
description | OBJECTIVE: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. METHODS: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders, followed in a university hospital in the Brazilian Northeast. Weight, height, and waist circumference were measured, and the lipid profile and glycated hemoglobin were analyzed. The hypertriglyceridemic waist phenotype was defined by the simultaneous presence of increased waist circumference (≥90(th) percentile for age and gender) and elevated serum triglyceride levels (≥75 mg/dL for children and ≥90 mg/dL for adolescents). We also investigated the family history of cardiovascular diseases and diabetes, as well as sociodemographic and behavioral variables. In the statistical inference tests, the proportions were compared by Pearson’s chi-square test and/or Fisher’s exact test, being significant p<0.05. RESULTS: A total of 102 patients were evaluated, most of them females (54.9%) and adolescents (66.7%). The frequency of hypertriglyceridemic waist was 23.5%, which was associated with females (p=0.043), overweight (p=0.023), hypercholesterolemia (p=0.002), high LDL (p=0.001), and borderline VLDL (<0.001). CONCLUSIONS: The frequency of the hypertriglyceridemic waist phenotype was associated with females, atherogenic lipid profile, and overweight, indicating the importance of the nutritional monitoring of this population, aiming at reducing future cardiovascular diseases. |
format | Online Article Text |
id | pubmed-7077793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade de Pediatria de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-70777932020-03-23 HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS Silva, Lílian Caroline de Souza e Silva, Skalyt Lee Barbosa e de Oliveira, Ávilla Monalisa Silva de Araujo, Jacqueline Rosangela de Arruda, Ilma Kruze Grande Maio, Regiane de Lemos, Maria da Conceição Chaves Rev Paul Pediatr Original Article OBJECTIVE: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. METHODS: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders, followed in a university hospital in the Brazilian Northeast. Weight, height, and waist circumference were measured, and the lipid profile and glycated hemoglobin were analyzed. The hypertriglyceridemic waist phenotype was defined by the simultaneous presence of increased waist circumference (≥90(th) percentile for age and gender) and elevated serum triglyceride levels (≥75 mg/dL for children and ≥90 mg/dL for adolescents). We also investigated the family history of cardiovascular diseases and diabetes, as well as sociodemographic and behavioral variables. In the statistical inference tests, the proportions were compared by Pearson’s chi-square test and/or Fisher’s exact test, being significant p<0.05. RESULTS: A total of 102 patients were evaluated, most of them females (54.9%) and adolescents (66.7%). The frequency of hypertriglyceridemic waist was 23.5%, which was associated with females (p=0.043), overweight (p=0.023), hypercholesterolemia (p=0.002), high LDL (p=0.001), and borderline VLDL (<0.001). CONCLUSIONS: The frequency of the hypertriglyceridemic waist phenotype was associated with females, atherogenic lipid profile, and overweight, indicating the importance of the nutritional monitoring of this population, aiming at reducing future cardiovascular diseases. Sociedade de Pediatria de São Paulo 2020-03-16 /pmc/articles/PMC7077793/ /pubmed/32187303 http://dx.doi.org/10.1590/1984-0462/2020/38/2019073 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article Silva, Lílian Caroline de Souza e Silva, Skalyt Lee Barbosa e de Oliveira, Ávilla Monalisa Silva de Araujo, Jacqueline Rosangela de Arruda, Ilma Kruze Grande Maio, Regiane de Lemos, Maria da Conceição Chaves HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title | HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND
ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title_full | HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND
ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title_fullStr | HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND
ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title_full_unstemmed | HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND
ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title_short | HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND
ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS |
title_sort | hypertriglyceridemic waist and associated factors in children and
adolescents with type 1 diabetes mellitus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077793/ https://www.ncbi.nlm.nih.gov/pubmed/32187303 http://dx.doi.org/10.1590/1984-0462/2020/38/2019073 |
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