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Systematic re-evaluation of the long-used standard protocol of urease-dependent metabolome sample preparation
In the urinary metabolomics for finding biomarkers in urine, owing to high concentrations of urea, for chromatography-based metabolomic analysis, urea needed to be degraded by urease. This urease pretreatment has been the key step of sample preparation for standard urinary metabolomics until today e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077817/ https://www.ncbi.nlm.nih.gov/pubmed/32182259 http://dx.doi.org/10.1371/journal.pone.0230072 |