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Systematic re-evaluation of the long-used standard protocol of urease-dependent metabolome sample preparation

In the urinary metabolomics for finding biomarkers in urine, owing to high concentrations of urea, for chromatography-based metabolomic analysis, urea needed to be degraded by urease. This urease pretreatment has been the key step of sample preparation for standard urinary metabolomics until today e...

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Detalles Bibliográficos
Autores principales: Kim, Jungyeon, Ahn, Joong Kyong, Cheong, Yu Eun, Lee, Sung-Joon, Cha, Hoon-Suk, Kim, Kyoung Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077817/
https://www.ncbi.nlm.nih.gov/pubmed/32182259
http://dx.doi.org/10.1371/journal.pone.0230072