Cargando…

Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae

Over 100 metabolic serine hydrolases are present in humans with confirmed functions in metabolism, immune response, and neurotransmission. Among potentially clinically-relevant but uncharacterized human serine hydrolases is OVCA2, a serine hydrolase that has been linked with a variety of cancer-rela...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bun, Jessica S., Slack, Michael D., Schemenauer, Daniel E., Johnson, R. Jeremy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077851/ https://www.ncbi.nlm.nih.gov/pubmed/32182256 http://dx.doi.org/10.1371/journal.pone.0230166

Ejemplares similares

Serine ADP-ribosylation reversal by the hydrolase ARH3
por: Fontana, Pietro, et al.
Publicado: (2017)

Proteomic characterization of serine hydrolase activity and composition in normal urine
por: Navarrete, Mario, et al.
Publicado: (2013)

Serine Hydrolases in Lipid Homeostasis of the Placenta-Targets for Placental Function?
por: Berger, Natascha, et al.
Publicado: (2022)

Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
por: Fellner, Matthias
Publicado: (2021)

Click-generated triazole ureas as ultrapotent, in vivo-active serine hydrolase inhibitors
por: Adibekian, Alexander, et al.
Publicado: (2011)

The roles of serine hydrolases and serum albumin in alisol B 23-acetate hydrolysis in humans
por: Zhang, Tiantian, et al.
Publicado: (2023)

The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis
por: Farberg, Alexander M., et al.
Publicado: (2016)

Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets
por: Davison, Dara, et al.
Publicado: (2022)

The Toxoplasma gondii Active Serine Hydrolase 4 Regulates Parasite Division and Intravacuolar Parasite Architecture
por: Foe, Ian T., et al.
Publicado: (2018)

Activity based protein profiling to detect serine hydrolase alterations in virus infected cells
por: Shahiduzzaman, Md., et al.
Publicado: (2012)

Activity-based protein profiling of rice (Oryza sativa L.) bran serine hydrolases
por: Dolui, Achintya Kumar, et al.
Publicado: (2020)

Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12
por: Ahonen, Tiina J., et al.
Publicado: (2023)

The PE16 (Rv1430) of Mycobacterium tuberculosis Is an Esterase Belonging to Serine Hydrolase Superfamily of Proteins
por: Sultana, Rafiya, et al.
Publicado: (2013)

Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone
por: Lajkiewicz, Neil J., et al.
Publicado: (2014)

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain
por: van Rooden, Eva J., et al.
Publicado: (2018)

The serine hydrolase ABHD6 controls survival and thermally induced seizures in a mouse model of Dravet syndrome
por: Westenbroek, Ruth, et al.
Publicado: (2023)

Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes
por: Lanier, Marion, et al.
Publicado: (2017)

Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation
por: Lim, Seakcheng, et al.
Publicado: (2020)

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors
por: Savinainen, J R, et al.
Publicado: (2012)

The PE-PPE Domain in Mycobacterium Reveals a Serine α/β Hydrolase Fold and Function: An In-Silico Analysis
por: Sultana, Rafiya, et al.
Publicado: (2011)

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation
por: Viader, Andreu, et al.
Publicado: (2016)

Erratum for Foe et al., “The Toxoplasma gondii Active Serine Hydrolase 4 Regulates Parasite Division and Intravacuolar Parasite Architecture”
por: Foe, Ian T., et al.
Publicado: (2018)

Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids
por: Joshi, Alaumy, et al.
Publicado: (2018)

Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad
por: Kiss-Szemán, Anna J., et al.
Publicado: (2022)

First Identification of a Large Set of Serine Hydrolases by Activity-Based Protein Profiling in Dibutyl Phthalate-Exposed Zebrafish Larvae
por: Yedji, Rodrigue S., et al.
Publicado: (2022)

Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesterase
por: Legler, Patricia M., et al.
Publicado: (2014)

Kinetically-controlled mechanism-based isolation of metabolic serine hydrolases in active form from complex proteomes: butyrylcholinesterase as a case study
por: Liu, Hui, et al.
Publicado: (2019)

Biochemical Characterization of a Novel α/β-Hydrolase/FSH from the White Shrimp Litopenaeus vannamei
por: Garcia-Orozco, Karina D., et al.
Publicado: (2019)

Human Valacyclovir Hydrolase/Biphenyl Hydrolase-Like Protein Is a Highly Efficient Homocysteine Thiolactonase
por: Marsillach, Judit, et al.
Publicado: (2014)

Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes
por: Rutherford, Nicola J., et al.
Publicado: (2016)

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils
por: Aaltonen, Niina, et al.
Publicado: (2020)

Distribution of Hydrolases among Anterior Pituitary Cell Fractions (Anterior Pituitary Hydrolases)
por: LaBella, Frank S., et al.
Publicado: (1958)

Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
por: Esch, Bianca M., et al.
Publicado: (2020)

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)

Discovery and rational engineering of PET hydrolase with both mesophilic and thermophilic PET hydrolase properties
por: Hong, Hwaseok, et al.
Publicado: (2023)

Sugar Promotes Feeding in Flies via the Serine Protease Homolog scarface
por: Prasad, Naveen, et al.
Publicado: (2018)

Prevalence and Homology of the Pneumococcal Serine-Rich Repeat Protein at the Global Scale
por: Aceil, Javid, et al.
Publicado: (2023)

Resistance to serine in Bacillus subtilis: identification of the serine transporter YbeC and of a metabolic network that links serine and threonine metabolism
por: Klewing, Anika, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_sc5sjsk1i8cficfuurg652n74s