Cargando…

Generation of Antitumor T Cells For Adoptive Cell Therapy With Artificial Antigen Presenting Cells

Adoptive cell therapy with ex vivo expanded tumor infiltrating lymphocytes or gene engineering T cells expressing chimeric antigen receptors (CAR) is a promising treatment for cancer patients. This production utilizes T-cell activation and transduction with activation beads and RetroNectin, respecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shrestha, Bishwas, Zhang, Yongliang, Yu, Bin, Li, Gongbo, Boucher, Justin C., Beatty, Nolan J., Tsai, Ho-Chien, Wang, Xuefeng, Mishra, Asmita, Sweet, Kendra, Lancet, Jeffrey E., Kelley, Linda, Davila, Marco L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077957/ https://www.ncbi.nlm.nih.gov/pubmed/31834208 http://dx.doi.org/10.1097/CJI.0000000000000306

Ejemplares similares

Large Scale Ex Vivo Expansion of γδ T cells Using Artificial Antigen-presenting Cells
por: Boucher, Justin C., et al.
Publicado: (2023)

CD3 engagement as a new strategy for allogeneic “off-the-shelf” T cell therapy
por: Li, Gongbo, et al.
Publicado: (2022)

Berberine displays antitumor activity in esophageal cancer cells in vitro
por: Jiang, Shu-Xian, et al.
Publicado: (2017)

Intra-arterial Versus Intravenous Adoptive Cell Therapy in a Mouse Tumor Model
por: Visioni, Anthony, et al.
Publicado: (2018)

Anti-TGF-β Antibody Combined with Dendritic Cells Produce Antitumor Effects in Osteosarcoma
por: Kawano, Masanori, et al.
Publicado: (2012)

Therapeutic Antitumor Efficacy of B Cells Loaded With Tumor-derived Autophagasomes Vaccine (DRibbles)
por: Ren, Hongyan, et al.
Publicado: (2014)

Nicotinic receptors modulate antitumor therapy response in triple negative breast cancer cells
por: Español, Alejandro, et al.
Publicado: (2022)

Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
por: Kalim, Khalid W, et al.
Publicado: (2022)

STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells
por: Qi, Ming-Ming, et al.
Publicado: (2021)

Single-cell sequencing reveals antitumor characteristics of intratumoral immune cells in old mice
por: Zhang, Cangang, et al.
Publicado: (2021)

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity
por: Efimova, Iuliia, et al.
Publicado: (2020)

CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell
por: Wang, Binglin, et al.
Publicado: (2021)

Adoptive Transfer of Interleukin-21-stimulated Human CD8(+) T Memory Stem Cells Efficiently Inhibits Tumor Growth
por: Chen, Yingshi, et al.
Publicado: (2018)

Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib
por: Qin, Jim S., et al.
Publicado: (2020)

Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity
por: Wang, Zining, et al.
Publicado: (2021)

Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
por: Liu, Xia, et al.
Publicado: (2022)

Effect of different artificial tears against desiccation in cultured human epithelial cells
por: Tost, Frank, et al.
Publicado: (2012)

Immunomodulatory, Apoptosis Induction and Antitumor Activities of Aqueous and Methanolic Extract of Calvatia Craniiformis in Mice Transfected with Murine Hepatocellular Carcinoma Cells
por: Jameel, Ghassan Hamdan, et al.
Publicado: (2018)

The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer
por: Cho, Sung Ho, et al.
Publicado: (2017)

Antitumor and apoptotic effects of 5-methoxypsoralen in U87MG human glioma cells and its effect on cell cycle, autophagy and PI3K/Akt signaling pathway
por: Guo, Haixia, et al.
Publicado: (2019)

Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
por: Chen, Heyu, et al.
Publicado: (2020)

Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells
por: Zhao, Songbo, et al.
Publicado: (2021)

Estrogen receptor beta signaling in CD8(+) T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch
por: Yuan, Bin, et al.
Publicado: (2021)

Tumor-associated Tregs obstruct antitumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells
por: Noyes, David, et al.
Publicado: (2022)

Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells
por: Bai, Xiaowu, et al.
Publicado: (2022)

Dual receptor T cells mediate effective antitumor immune responses via increased recognition of tumor antigens
por: Jang, Hyun J, et al.
Publicado: (2023)

Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity
por: Fernandez-Rodriguez, Laura, et al.
Publicado: (2023)

Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity
por: Shah, Sabaria, et al.
Publicado: (2023)

Preferential Homing of Tumor-specific and Functional CD8(+) Stem Cell-like Memory T Cells to the Bone Marrow
por: Wu, Kang, et al.
Publicado: (2019)

TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8(+) T cell and XCR1(+) dendritic cell spatial co-localization
por: Gardner, Alycia, et al.
Publicado: (2022)

Enrichment and expansion with nanoscale artificial antigen presenting cells for T cell adoptive immunotherapy
por: Perica, Karlo, et al.
Publicado: (2014)

Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions
por: Hu, Jie, et al.
Publicado: (2013)

Amino acids and RagD potentiate mTORC1 activation in CD8(+) T cells to confer antitumor immunity
por: Zhang, Yiwen, et al.
Publicado: (2021)

Oral SMEDDS promotes lymphatic transport and mesenteric lymph nodes target of chlorogenic acid for effective T-cell antitumor immunity
por: Ye, Jun, et al.
Publicado: (2021)

Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
por: Deng, Guoliang, et al.
Publicado: (2022)

TFAM deficiency in dendritic cells leads to mitochondrial dysfunction and enhanced antitumor immunity through cGAS-STING pathway
por: Lu, Tianqi, et al.
Publicado: (2023)

Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A
por: Li, Xian, et al.
Publicado: (2022)

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells
por: Lee, Ping-Hsien, et al.
Publicado: (2019)

CD25-targeted antibody–drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity
por: Zammarchi, Francesca, et al.
Publicado: (2020)

Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
por: Niogret, Julie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5gd3th2deurbrvdkpggevq80jv