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Multiplex Screening Assay for Identifying Cytotoxic CD8(+) T Cell Epitopes

The cytotoxicity of epitope-specific CD8(+) T cells is usually measured indirectly through IFNγ production. Existing assays that directly measure this activity are limited mainly to measurements of up to two specificities in a single reaction. Here, we develop a multiplex cytotoxicity assay that all...

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Detalles Bibliográficos
Autores principales:	Poh, Chek Meng, Zheng, Jian, Channappanavar, Rudragouda, Chang, Zi Wei, Nguyen, Thi H. O., Rénia, Laurent, Kedzierska, Katherine, Perlman, Stanley, Poon, Leo L. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078160/ https://www.ncbi.nlm.nih.gov/pubmed/32218786 http://dx.doi.org/10.3389/fimmu.2020.00400

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