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Repurposing Clinical Drugs as AdoMetDC Inhibitors Using the SCAR Strategy
With the escalating costs in drug development, discovering new uses of approved drugs, i.e., drug repurposing, has attracted increasing interest. Spermidine and spermine are important polyamines for most cells and their biosynthesis are strictly regulated by the polyamine metabolic network. In cance...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078168/ https://www.ncbi.nlm.nih.gov/pubmed/32218733 http://dx.doi.org/10.3389/fphar.2020.00248 |