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Apatinib Inhibits Cell Proliferation and Induces Autophagy in Human Papillary Thyroid Carcinoma via the PI3K/Akt/mTOR Signaling Pathway

Background: Patients with metastatic radioiodine-refractory papillary thyroid carcinoma (PTC) have limited treatment options and a poor prognosis. There is an urgent need to develop new drugs targeting PTC for clinical application. Apatinib, a novel small-molecule tyrosine kinase inhibitor (TKI), is...

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Detalles Bibliográficos
Autores principales:	Meng, Xiangrui, Wang, Huijuan, Zhao, Jingzhu, Hu, Linfei, Zhi, Jingtai, Wei, Songfeng, Ruan, Xianhui, Hou, Xiukun, Li, Dapeng, Zhang, Jun, Yang, Weiwei, Qian, Biyun, Wu, Yu, Zhang, Yuan, Meng, Zhaowei, Guan, Lizhao, Zhang, Huilai, Zheng, Xiangqian, Gao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078169/ https://www.ncbi.nlm.nih.gov/pubmed/32219060 http://dx.doi.org/10.3389/fonc.2020.00217

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