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Pre-operative cellular dissociation grading in biopsies is highly predictive of post-operative tumour stage and patient outcome in head and neck squamous cell carcinoma
BACKGROUND: Pre-operative treatment planning in head and neck squamous cell carcinoma (HNSCC) is mainly dictated by clinical staging, which has major shortcomings. Histologic grading is irrelevant due to its lack of prognostic impact. Recently, a novel grading termed Cellular Dissociation Grade (CDG...
Autores principales: | Jesinghaus, Moritz, Steiger, Katja, Stögbauer, Fabian, Haller, Bernhard, Kolk, Andreas, Straßen, Ulrich, Pickhard, Anja, Wirth, Markus, Silva, Miguel, Budczies, Jan, Becker von Rose, Aaron, Konukiewitz, Björn, Kuhn, Peer, Klinghammer, Konrad, Dapper, Hendrik, Münch, Stefan, Combs, Stephanie E., Weichert, Wilko, Boxberg, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078181/ https://www.ncbi.nlm.nih.gov/pubmed/31937923 http://dx.doi.org/10.1038/s41416-019-0719-8 |
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