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A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer
Glucose metabolism is remodeled in cancer, but the global pattern of cancer-specific metabolic changes remains unclear. Here we show, using the comprehensive measurement of metabolic enzymes by large-scale targeted proteomics, that the metabolism both carbon and nitrogen is altered during the malign...
Autores principales: | Kodama, Manabu, Oshikawa, Kiyotaka, Shimizu, Hideyuki, Yoshioka, Susumu, Takahashi, Masatomo, Izumi, Yoshihiro, Bamba, Takeshi, Tateishi, Chisa, Tomonaga, Takeshi, Matsumoto, Masaki, Nakayama, Keiichi I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078194/ https://www.ncbi.nlm.nih.gov/pubmed/32184390 http://dx.doi.org/10.1038/s41467-020-15136-9 |
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