Preoperative detection of KRAS G12D mutation in ctDNA is a powerful predictor for early recurrence of resectable PDAC patients

BACKGROUND: About 25–37% of resectable pancreatic ductal adenocarcinoma (PDAC) had a great chance of early recurrence after radical resection, which is mainly due to preoperative micrometastasis. We herein demonstrated the profiles of ctDNA in resectable PDAC and use of ctDNA to identify patients wi...

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Detalles Bibliográficos
Autores principales: Guo, Shiwei, Shi, Xiaohan, Shen, Jing, Gao, Suizhi, Wang, Huan, Shen, Shuo, Pan, Yaqi, Li, Bo, Xu, Xiongfei, Shao, Zhuo, Jin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078253/
https://www.ncbi.nlm.nih.gov/pubmed/31969677
http://dx.doi.org/10.1038/s41416-019-0704-2

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