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Gating mechanism of hyperpolarization-activated HCN pacemaker channels

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are essential for rhythmic activity in the heart and brain, and mutations in HCN channels are linked to heart arrhythmia and epilepsy. HCN channels belong to the family of voltage-gated K(+) (Kv) channels. However, why HCN channels a...

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Detalles Bibliográficos
Autores principales:	Ramentol, Rosamary, Perez, Marta E., Larsson, H. Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078272/ https://www.ncbi.nlm.nih.gov/pubmed/32184399 http://dx.doi.org/10.1038/s41467-020-15233-9

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