Grasp55(−/−) mice display impaired fat absorption and resistance to high-fat diet-induced obesity

The Golgi apparatus plays a central role in the intracellular transport of macromolecules. However, molecular mechanisms of Golgi-mediated lipid transport remain poorly understood. Here, we show that genetic inactivation of the Golgi-resident protein GRASP55 in mice reduces whole-body fat mass via i...

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Detalles Bibliográficos
Autores principales: Kim, Jiyoon, Kim, Hyeyon, Noh, Shin Hye, Jang, Dong Geon, Park, Shi-Young, Min, Dongkook, Kim, Hyunki, Kweon, Hee-Seok, Kim, Hoguen, Aum, Sowon, Seo, Sookyung, Choi, Cheol Soo, Kim, Hail, Kim, Jae Woo, Moon, Seok Jun, Gee, Heon Yung, Lee, Min Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078302/
https://www.ncbi.nlm.nih.gov/pubmed/32184397
http://dx.doi.org/10.1038/s41467-020-14912-x

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