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Cytosolic Ca(2+) Modulates Golgi Structure Through PKCα-Mediated GRASP55 Phosphorylation

It has been well documented that the ER responds to cellular stresses through the unfolded protein response (UPR), but it is unknown how the Golgi responds to similar stresses. In this study, we treated HeLa cells with ER stress inducers, thapsigargin (TG), tunicamycin (Tm), and dithiothreitol (DTT)...

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Detalles Bibliográficos
Autores principales: Ireland, Stephen, Ramnarayanan, Saiprasad, Fu, Mingzhou, Zhang, Xiaoyan, Zhang, Jianchao, Li, Jie, Emebo, Dabel, Wang, Yanzhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078314/
https://www.ncbi.nlm.nih.gov/pubmed/32179476
http://dx.doi.org/10.1016/j.isci.2020.100952